PMID: 9449779Jan 1, 1997Paper

Antimicrobial effects of the macrocyclic Cu(II)-tetraanhydroaminobenzaldehyde complex

Folia Microbiologica
S JantováM Zastková

Abstract

The Cu(II)-tetraaza macrocyclic complex exhibited antimicrobial effects on bacteria, yeasts and filamentous fungi. The highest antibacterial activity was found with B. subtilis and S. aureus, the respective IC50 values being 18 and 80 micrograms/L and the MIC values 50 and 1000 micrograms/L. A concentration of 1 mg/L exerted a bacteriocide effect on S. aureus. The MIC value for B. subtilis was 250 times lower and for P. aeruginosa 10 times lower than the corresponding values for ampicillin. The Cu-complex was inactive against all tested yeasts. The strongest antifungal effect was manifested for R. nigricans, with an IC50 value under 0.1 mg/L, whereas in A. alternata the IC50 was 13.5 mg/L.

Citations

Mar 20, 2002·Folia Microbiologica·B DudováM Melník
Apr 3, 1999·Folia Microbiologica·R GottasováL Cipák
Aug 23, 2005·Folia Microbiologica·S JantováS Stankovský
Aug 1, 1999·Toxicology in Vitro : an International Journal Published in Association with BIBRA·M Urbančíková, P Korytár

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