Antimicrobial efficacy of drug blended biosynthesized colloidal gold nanoparticles from Justicia glauca against oral pathogens: A nanoantibiotic approach

Microbial Pathogenesis
R EmmanuelPeriyakaruppan Prakash

Abstract

Antimicrobial resistance is a challenging task for researchers to develop new strategies. Green synthesis of AuNPs is an eco-friendly approach, which can be utilized in the microbistatic and microbicidal activities. The current study is focused on Justicia glauca (aqueous leaf extract) mediated AuNPs synthesis at room temperature by treating chloroaurate ions, that shows an antagonistic effect with Azithromycin (AZM) and Clarithromycin (CLR) antibiotics against oral pathogenic bacteria and fungi (Micrococcus luteus, Bacillus subtilis, Staphylococcus aureus, Streptococcus mutans, Lactobacillus acidophilus, Escherichia coli, Pseudomonas aeruginosa, Saccharomyces cerevisiae and Candida albicans). Characterization of green synthesized AuNPs was done by using Ultraviolet-visible (UV-vis) spectroscopy, Fourier Transform Infrared (FTIR) spectroscopy, Transmission Electron Microscopy (TEM), X-Ray Diffraction (XRD) analysis and Energy Dispersive X-ray analysis (EDAX). Biosynthesized AuNPs were stable, hexagonal and spherical shaped with a size ∼32.5 ± 0.25 nm. The AuNPs and drug conjugated AuNPs showed potential antibacterial and antifungal activity against the oral pathogens. Minimum Inhibitory Concentration (MIC) values of biogenic Au...Continue Reading

Citations

Mar 8, 2018·Artificial Cells, Nanomedicine, and Biotechnology·Vasudeva Reddy NetalaVijaya Tartte
Jul 11, 2019·Nanotechnology·Luciana Betzler de Oliveira de SiqueiraEduardo Ricci Junior
Sep 24, 2019·Recent Patents on Drug Delivery & Formulation·Rachna RanaGiriraj T Kulkarni
Apr 1, 2020·Current Topics in Medicinal Chemistry·Pawan KaurAlok Adholeya
Nov 9, 2018·Frontiers in Aging Neuroscience·Muhammad OvaisZabta Khan Shinwari
Dec 21, 2018·International Journal of Molecular Sciences·Muhammad OvaisSudip Mukherjee
Mar 29, 2018·Applied Microbiology and Biotechnology·Muhammad OvaisZabta Khan Shinwari
Jun 9, 2018·Applied Microbiology and Biotechnology·Muhammad OvaisSudip Mukherjee
Oct 17, 2019·Microscopy Research and Technique·Nosheen FerozeAsma Ayaz
Jan 14, 2021·Journal of Food Science·Khaing Zar MyintJie Shen
Oct 31, 2020·Frontiers in Microbiology·Cinthia Alves-BarrocoPedro Viana Baptista
Feb 2, 2021·Biocatalysis and Agricultural Biotechnology·Tariq KhanAkhtar Nadhman
Jun 11, 2021·Frontiers in Microbiology·Khristina G Judan CruzKozo Watanabe
Oct 27, 2021·Advanced Drug Delivery Reviews·Sajid AsgharThierry F Vandamme
Jul 1, 2020·Mini Reviews in Medicinal Chemistry·Hsuan HsuVeronica Veses

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Candida albicans

Candida albicans is an opportunistic, fungal pathogen of humans that frequently causes superficial infections of oral and vaginal mucosal surfaces of debilitated and susceptible individuals. Discover the latest research on Candida albicans here.

Candidiasis

Candidiasis is a common fungal infection caused by Candida and it can affect many parts for the body including mucosal membranes as well as the gastrointestinal, urinary, and respiratory tracts. Here is the latest research.

Candidiasis (ASM)

Candidiasis is a common fungal infection caused by Candida and it can affect many parts for the body including mucosal membranes as well as the gastrointestinal, urinary, and respiratory tracts. Here is the latest research.

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.