Antimicrobial eugenol nanoemulsion prepared by gum arabic and lecithin and evaluation of drying technologies

International Journal of Biological Macromolecules
Qiaobin HuYangchao Luo

Abstract

The purpose of present work was to develop eugenol oil nanoemulsions using gum arabic and lecithin as food grade natural emulsifiers, and study their antimicrobial activity. In addition, our study also evaluated different drying techniques (spray drying and freeze drying) on the morphology and redispersibility of nanoemulsion powders. The optimal fabrication method, physicochemical and structural characterization, stability, and antimicrobial activity were investigated. Results showed that nanoemusions with a particle size of 103.6±7.5nm were obtained by mixing aqueous phase (0.5% gum arabic, 0.5% lecithin, w/v) and eugenol oil (1.25%, w/v), which was premixed with ethanol (as a co-surfactant), followed by high speed homogenization process. The molecular interactions among emulsifiers and eugenol were evidenced by Fourier transform infrared spectroscopy. Buchi B-90 Nano Spray Dryer was evaluated as a powerful tool to obtain ultrafine spherical powders with a size of less than 500nm, compared to flake-like aggregation obtained by freeze-drying. The dried powders exhibited excellent re-dispersibility in water and maintained their physicochemical properties after re-hydration. The nanoemulsions did not adversely affect the antimic...Continue Reading

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Citations

Jul 30, 2016·European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Für Pharmazeutische Verfahrenstechnik E.V·Taoran WangYangchao Luo
Aug 1, 2016·International Journal of Biological Macromolecules·Qiaobin HuYangchao Luo
Jun 9, 2018·Critical Reviews in Food Science and Nutrition·Elham Assadpour, Seid Mahdi Jafari
Jan 17, 2019·Annual Review of Food Science and Technology·Elham Assadpour, Seid Mahdi Jafari
Nov 27, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Qingqing LiuQin Wang
Feb 17, 2019·Membranes·Souhir SabriViktor Kochkodan
Nov 21, 2019·Nanomaterials·Danijel D MilinčićMirjana B Pešić
Dec 20, 2020·International Journal of Biological Macromolecules·Leandra Oliveira XavierMichael Ramos Nunes
Nov 1, 2020·International Journal of Biological Macromolecules·Cynthia Lizeth Barrera-MartínezRené Darío Peralta-Rodríguez
Dec 19, 2020·Comprehensive Reviews in Food Science and Food Safety·Ilyes DammakCarlos Adam Conte-Junior
Feb 29, 2020·International Journal of Biological Macromolecules·Sahil ChaudharyRakesh Sharma
Dec 19, 2017·Advances in Colloid and Interface Science·David Julian McClements, Seid Mahdi Jafari
Jul 10, 2021·Regulatory Toxicology and Pharmacology : RTP·SiMin WeiJinGui Li
Aug 14, 2021·Advances in Colloid and Interface Science·Seyedeh Narges JamaliSeid Mahdi Jafari
Aug 25, 2021·International Journal of Biological Macromolecules·Fuyu SongHaisong Wang
Sep 23, 2021·Assay and Drug Development Technologies·A Alper Öztürk, Cordin Arpagaus
Nov 28, 2020·Current Drug Delivery·Sonia TrombinoRoberta Cassano

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