Antimicrobial evaluation of 1-methyl-3-nitro-1-Nitrosoguanidine.

Applied Microbiology
D E Hunt, R F Pittillo

Abstract

1-Methyl-3-nitro-1-nitrosoguanidine was shown to have in vitro antimicrobial activity against fungi and gram-positive and gram-negative bacteria; it was also shown to have in vivo activity in mice experimentally infected with Staphylococcus aureus or Escherichia coli comparable to that observed with penicillin or streptomycin sulfate.

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