Antimicrobial peptides from different plant sources: Isolation, characterisation, and purification

Phytochemistry
Swee-Seong TangShamala D Sekaran

Abstract

Antimicrobial peptides (AMPs), the self-defence products of organisms, are extensively distributed in plants. They can be classified into several groups, including thionins, defensins, snakins, lipid transfer proteins, glycine-rich proteins, cyclotides and hevein-type proteins. AMPs can be extracted and isolated from different plants and plant organs such as stems, roots, seeds, flowers and leaves. They perform various physiological defensive mechanisms to eliminate viruses, bacteria, fungi and parasites, and so could be used as therapeutic and preservative agents. Research on AMPs has sought to obtain more detailed and reliable information regarding the selection of suitable plant sources and the use of appropriate isolation and purification techniques, as well as examining the mode of action of these peptides. Well-established AMP purification techniques currently used include salt precipitation methods, absorption-desorption, a combination of ion-exchange and reversed-phase C18 solid phase extraction, reversed-phase high-performance liquid chromatography (RP-HPLC), and the sodium dodecyl sulphate polyacrylamide gel electrophoresis (SDS-PAGE) method. Beyond these traditional methods, this review aims to highlight new and diff...Continue Reading

Citations

Feb 19, 2019·Chemical Biology & Drug Design·Sima Sadat SeyedjavadiMehdi Razzaghi-Abyaneh
Nov 21, 2019·Current Protein & Peptide Science·Snober Shabeer WaniTanveer A Dar
Jul 25, 2019·Current Medicinal Chemistry·Bruno CasciaroMaria Luisa Mangoni
Jan 23, 2021·Critical Reviews in Food Science and Nutrition·Laila N ShwaikiKieran M Lynch
Nov 12, 2020·Journal of Pharmaceutical and Biomedical Analysis·Jérémy MolineauCaroline West
Mar 14, 2021·Bioorganic Chemistry·Mohammad Sadegh TaghizadehAli Reza Afsharifar
Apr 30, 2021·Botanical Studies·Junpeng LiXingyong Yang
Sep 27, 2019·Journal of Natural Products·Tessa B MoyerLeslie M Hicks
May 11, 2019·Biochimica Et Biophysica Acta. Biomembranes·Morgan A HitchnerGregory A Caputo
Oct 5, 2021·Journal of Applied Microbiology·Mine Erdem Büyükkiraz, Zülal Kesmen
Dec 17, 2021·Scientific Reports·Binish KhaliqAhmed Akrem

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