Antimicrobial potential of 1H -benzo[d ]imidazole scaffold: a review

BMC Chemistry
Sumit TahlanBalasubramanian Narasimhan

Abstract

Benzimidazole is a heterocyclic moiety whose derivatives are present in many of the bioactive compounds and posses diverse biological and clinical applications. Benzimidazole agents are the vital pharmacophore and privileged sub-structures in chemistry of medicine. They have received much interest in drug discovery because benzimidazoles exhibited enormous significance. So attempts have been made to create repository of molecules and evaluate them for prospective inherent activity. They are extremely effective both with respect to their inhibitory activity and favorable selectivity ratio. Benzimidazole is most promising category of bioactive heterocyclic compound that exhibit a wide variety of biological activities in medicinal field. The present review only focus on antimicrobial activity of reported benzimidazole derivatives may serve as valuable source of information for researchers who wish to synthesize new molecules of benzimidazole nucleus which have immense potential to be investigated for newer therapeutic possibilities.

References

May 15, 2002·European Journal of Medicinal Chemistry·Vera KlimesováJarmila Kaustová
Nov 25, 2003·Il Farmaco·Gülgün Ayhan-Kilcigil, Nurten Altanlar
Dec 31, 2003·Bioorganic & Medicinal Chemistry·Tatiana FonsecaErik De Clercq
Feb 6, 2004·European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences·Mariola AndrzejewskaZygmunt Kazimierczuk
Feb 25, 2005·Bioorganic & Medicinal Chemistry·A Khalafi-NezhadB Hemmateenejad
Jul 12, 2005·European Journal of Medicinal Chemistry·Farukh ArjmandShamim Ahmad
Mar 11, 2006·European Journal of Medicinal Chemistry·Bobba Venkata Siva KumarRamchandra Bhimrao Mane
Jun 13, 2006·European Journal of Medicinal Chemistry·José Luis FalcóAntonio Guglietta
Feb 10, 2007·Bioorganic & Medicinal Chemistry Letters·Ozden Ozel GüvenSulhiye Yildiz
Mar 21, 2007·Bioorganic & Medicinal Chemistry Letters·Anjani K TiwariV K Singh
Feb 2, 2008·Journal of Enzyme Inhibition and Medicinal Chemistry·Ilgar KerimovMümtaz Iscan
Mar 5, 2008·European Journal of Medicinal Chemistry·K F Ansari, C Lal
Jul 12, 2008·European Journal of Medicinal Chemistry·Datong ZhangJianwu Wang
Jan 3, 2009·Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy·Gehad G MohamedHanaa A E Attia
Feb 12, 2009·Bioorganic & Medicinal Chemistry Letters·Laixing HuNorman Abood
Jun 2, 2009·European Journal of Medicinal Chemistry·K F Ansari, C Lal
May 11, 2010·European Journal of Medicinal Chemistry·Yusuf OzkayIlhan Işikdağ
Jul 2, 2011·European Journal of Medicinal Chemistry·Rodrigo AboniaJusto Cobo
Apr 30, 2013·Bioorganic & Medicinal Chemistry·Kunal KumarIwao Ojima
Jul 11, 2013·International Journal of Antimicrobial Agents·Joao B MoreiraPeter W Taylor
Feb 22, 2014·European Journal of Medicinal Chemistry·Yaling GongGang Liu
Mar 13, 2014·European Journal of Medicinal Chemistry·D SeenaiahN Siva Krishna
Sep 23, 2014·Bioorganic & Medicinal Chemistry Letters·Sridhar MadabhushiC Ganesh Kumar
Feb 20, 2016·Journal of Pesticide Science·Weijie SiXiangdong Mei

❮ Previous
Next ❯

Citations

Apr 4, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Rafael T ArosoMariette M Pereira

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anthelmintics

Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. Discover the latest research on anthelmintics here.

Related Papers

Mini Reviews in Medicinal Chemistry
Kuldipsinh P BarotManjunath D Ghate
Mini Reviews in Medicinal Chemistry
Kuldipsinh P BarotManjunath D Ghate
Mini Reviews in Medicinal Chemistry
Ahmed A El Rashedy, Hassan Y Aboul-Enein
© 2021 Meta ULC. All rights reserved