Antimicrobial proteins and peptides in host defense

Seminars in Respiratory Infections
T Ganz

Abstract

The antimicrobial properties of airways secretions and other mucosal secretions have been known for more than 70 years. Recent studies have identified a number of antimicrobial peptides and proteins that contribute to the antimicrobial activity of secretions, both under basal and inflamed conditions. Several peptides have properties that make them suitable for pharmaceutical development as topical or systemic antimicrobial agents.

Citations

Oct 7, 2005·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·L U LahodaP M Vogt
Nov 15, 2002·Journal of Anatomy·J H Widdicombe
Oct 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·K A DaherM Kronenberg
Jul 2, 2010·The Journal of Biological Chemistry·Praveen PapareddyArtur Schmidtchen
Jan 25, 2012·The Journal of Biological Chemistry·Marzena PazgierWuyuan Lu
Jul 19, 2006·Clinical Microbiology Reviews·Håvard JenssenRobert E W Hancock
Jul 8, 2009·Infection and Immunity·Robert I LehrerWuyuan Lu
May 14, 2008·Infection and Immunity·Katharina BeiterBirgitta Henriques-Normark
Jun 18, 2002·Infection and Immunity·Catherine A Brissette, Sheila A Lukehart
Aug 1, 1989·The Journal of Clinical Investigation·R I LehrerM E Selsted
Dec 25, 2009·BMC Genomics·Oliver BruhnGeorg Thaller
Jul 17, 2009·BMC Research Notes·Mukesh PasupuletiArtur Schmidtchen
Oct 8, 2009·PloS One·Mukesh PasupuletiArtur Schmidtchen
Feb 24, 2012·PloS One·John David SpencerAndrew L Schwaderer
Sep 18, 2008·PLoS Pathogens·Victoria RydengårdArtur Schmidtchen
Nov 20, 2004·Proceedings of the National Academy of Sciences of the United States of America·Emma Andersson NordahlArtur Schmidtchen
Apr 25, 2007·Growth Factors·Martin MalmstenArtur Schmidtchen
Jul 20, 2005·Acta Obstetricia Et Gynecologica Scandinavica·Merete HeinJesper Reinholdt
Apr 2, 2005·Clinics in Chest Medicine·Carol M Mason, Steve Nelson
Mar 19, 2004·Pancreas·Danuta KruszewskaStefan G Pierzynowski
Aug 18, 2010·Periodontology 2000·Kazuyuki Ishihara
Aug 11, 2005·The Journal of Biological Chemistry·Emma Andersson NordahlArtur Schmidtchen
Oct 30, 2009·International Journal of Molecular Sciences·Lars SteinstraesserSammy Al-Benna
Nov 11, 2011·International Journal of Molecular Sciences·Garry LavertyBrendan F Gilmore
Oct 20, 2012·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Min-Duk SeoBong-Jin Lee
Sep 10, 2014·The Journal of Biological Chemistry·Praveen PapareddyArtur Schmidtchen
Dec 10, 2015·Proteomics·Pramod ShahChien-Sheng Chen
May 19, 2017·FEMS Microbiology Reviews·María Eugenia Pachón-IbáñezJavier Sánchez-Céspedes
May 31, 2002·Nature·Pradeep K SinghMichael J Welsh
Aug 6, 2003·FEMS Immunology and Medical Microbiology·Louise A DuitsPieter S Hiemstra
Jun 24, 2004·The Journal of Immunology : Official Journal of the American Association of Immunologists·Wei WangRobert I Lehrer
Nov 20, 2016·The Journal of Obstetrics and Gynaecology Research·Seungho LeeNohhyun Park
Aug 7, 2007·Clinica Chimica Acta; International Journal of Clinical Chemistry·Hendrik Schultz, Jerrold P Weiss

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