Antimicrobial resistance and virulence markers in methicillin sensitive Staphylococcus aureus isolates associated with nasal colonization

Microbial Pathogenesis
Abdullah SarkarAbiola Senok

Abstract

Most Staphylococcus aureus infections occur in previously colonized persons who also act as reservoirs for continued dissemination. This study aimed to investigate the carriage of antimicrobial resistance and virulence markers in S. aureus isolates associated with nasal colonization. The study was conducted from December 2013-April 2014. Nasal swabs were collected and questionnaires administered to 97 medical students in Riyadh Saudi Arabia. Bacterial culture, identification and antimicrobial susceptibility testing were performed by conventional methods and chromogenic agar was used for methicillin resistant S. aureus (MRSA) screening. Molecular characterization of isolates was carried out using the StaphyType DNA microarray. Thirty two students (43%) had S. aureus nasal carriage (MSSA = 31; MRSA = 1). Seventeen clonal complexes (CC) were identified namely: CC15-MSSA (n = 5), CC1-MSSA-SCCfus (n = 4), CC8-MSSA (n = 3), CC22-MSSA (n = 3), CC25-MSSA (n = 3), CC101-MSSA (n = 2). Other CC found as single isolates were CC5-MSSA, CC6-MSSA, CC30-MSSA, CC45-MSSA, CC96-MSSA, CC188-MSSA, CC398-MSSA, CC942-MSSA/PVL+, CC1290-MSSA, ST2482-MSSA, CC80-MRSA-IV/PVL+. The CC1-SCCfus isolates harbored the Staphylococcal cassette chromosome (SCC) w...Continue Reading

References

Aug 26, 1998·The New England Journal of Medicine·F D Lowy
Jan 9, 1999·The New England Journal of Medicine·S BlotF Colardyn
Jan 2, 2001·Transactions of the Royal Society of Tropical Medicine and Hygiene·A A AlghaithyA H Weily
Jan 11, 2003·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Cassandra D SalgadoDavid P Calfee
Jul 10, 2004·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Werner E BischoffRobert J Sherertz
Mar 8, 2005·Journal of Clinical Microbiology·Arjanne van GriethuysenJan Kluytmans
Sep 13, 2005·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·S Monecke, R Ehricht
Mar 30, 2007·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·R H DeurenbergE E Stobberingh
Oct 18, 2007·JAMA : the Journal of the American Medical Association·R Monina KlevensUNKNOWN Active Bacterial Core surveillance (ABCs) MRSA Investigators
Apr 22, 2008·The Journal of Infectious Diseases·Rachel J GorwitzMatthew J Kuehnert
Oct 16, 2009·Clinical Laboratory Science : Journal of the American Society for Medical Technology·Rodney E RohdeAaron Brannon
Feb 2, 2010·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Gonzalo M L BearmanRichard P Wenzel
Jun 4, 2010·Journal of Clinical Microbiology·Olga SakwinskaPhilippe Moreillon
Mar 1, 2011·Veterinary Microbiology·Stefan MoneckeUlrich Wernery
Apr 6, 2011·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·N GardellaM Mollerach
Jul 25, 2013·International Journal of Antimicrobial Agents·Zahra MoravvejSareh Saadat

❮ Previous
Next ❯

Citations

Jan 8, 2020·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·Abiola SenokRalf Ehricht
Mar 17, 2018·Annals of Clinical Microbiology and Antimicrobials·Khaled R AlkharsahAmein K Al-Ali
May 3, 2021·Antimicrobial Resistance and Infection Control·Bahareh HajikhaniMasoud Dadashi

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Antimicrobial Resistance (ASM)

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.

Carcinoma, Squamous Cell

Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.

Antimicrobial Resistance

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.

CRISPR & Staphylococcus

CRISPR-Cas system enables the editing of genes to create or correct mutations. Staphylococci are associated with life-threatening infections in hospitals, as well as the community. Here is the latest research on how CRISPR-Cas system can be used for treatment of Staphylococcal infections.

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.