Antimicrobial resistance in Irish isolates of verocytotoxigenic Escherichia coli (E. coli)--VTEC

International Journal of Food Microbiology
C WalshD A McDowell

Abstract

This study compared the antimicrobial resistance profiles of Escherichia coli O157:H7 isolates (n=257) recovered from bovine hides, minced beef and human clinical samples in Ireland, to those profiles of a range of Irish non-O157 E. coli (O111 and O26) isolates (n=31) from a variety of clinical and veterinary sources. Four multi-drug resistant (MDR) E. coli O157:H7 food isolates were identified, with resistance to 10 (1 isolate), 6 (1 isolate) and 4 (2 isolates) antimicrobial agents, respectively. Two of these isolates (resistant to 7 and 4 antimicrobial classes) were characterised further by molecular methods and found to contain class 1 integrons along with a beta-lactamase-encoding tem-1 gene. Transfer of antimicrobial resistance (ampicillin, streptomycin and sulphonamides), the tem-1 gene and markers (int1, qacEDelta1, sul1) characteristic of class 1 integrons were evident in one MDR isolate (resistant to 4 antimicrobial classes) when conjugation and transformation experiments were performed. A clinical isolate and a veterinary isolate of the O111 serotype were MDR and resistant to 4 and 3 antimicrobial classes, respectively. These data suggest that the prevalence of antimicrobial resistance among the three VTEC serotypes e...Continue Reading

References

Jan 1, 1995·Antimicrobial Agents and Chemotherapy·C LévesqueP H Roy
Sep 1, 1997·Nucleic Acids Research·S F AltschulD J Lipman
Jun 16, 2000·International Journal of Antimicrobial Agents·J MurakamiM Nasu
Apr 20, 2001·Journal of Applied Microbiology·D WalshD A McDowell
Feb 2, 2002·Applied and Environmental Microbiology·Carl M SchroederJianghong Meng
Feb 5, 2002·Journal of Clinical Microbiology·Maria MiragaiaHermínia de Lencastre
Jul 18, 2002·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·D G WhiteC DebRoy
Oct 22, 2002·Journal of the American Veterinary Medical Association·Susan SanchezMichael P Doyle
Nov 28, 2002·Journal of Clinical Microbiology·Giovanni M GiammancoGiuseppe Giammanco
Jun 25, 2004·Antimicrobial Agents and Chemotherapy·Xian-Zhi LiHiroshi Nikaido
Jul 3, 2004·The Journal of Antimicrobial Chemotherapy·C M YatesS G B Amyes
Feb 17, 2005·Journal of Medical Microbiology·Ashraf M AhmedTadashi Shimamoto
Mar 17, 2005·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·Adrienne T A BoxAd C Fluit

❮ Previous
Next ❯

Citations

Jun 30, 2007·Foodborne Pathogens and Disease·Peter Gerner-SmidtElaine Scallan
Aug 31, 2007·International Journal of Food Microbiology·A DambrosioG Normanno
Mar 1, 2006·International Journal of Food Microbiology·G DuffyD A McDowell
Dec 24, 2008·Animal Health Research Reviews·Trudy M Wassenaar, Peter Silley

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Aminoglycosides

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

Aminoglycosides (ASM)

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

BioHub - Researcher Network

The Chan-Zuckerberg Biohub aims to support the fundamental research and develop the technologies that will enable physicians to cure, prevent, or manage all diseases in our childrens' lifetimes. The CZ Biohub brings together researchers from UC Berkeley, Stanford, and UCSF. Find the latest research from the CZ Biohub researcher network here.

Antimicrobial Resistance (ASM)

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.

Antimicrobial Resistance

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.