Antimicrobial Resistance of Neisseria Gonorrhoeae in a Newly Implemented Surveillance Program in Uganda: Surveillance Report.

JMIR Public Health and Surveillance
Meklit WorknehYukari C Manabe

Abstract

Neisseria gonorrhoeae (commonly known as gonorrhea) has developed resistance to all first-line therapy in Southeast Asia. East Africa has historically had absent or rudimentary gonorrhea surveillance programs and, while the existence of antimicrobial-resistant gonorrhea is recognized, the extent of its resistance is largely unknown. In 2016, the World Health Organization's Enhanced Gonococcal Antimicrobial Surveillance Program (EGASP) was initiated in Uganda to monitor resistance trends. This study characterizes gonorrhea and antibiotic resistance in a large surveillance program of men with urethral discharge syndrome from Kampala, Uganda. Men attending sentinel clinics with urethritis provided demographic information, behavior data, and a urethral swab in line with the World Health Organization's EGASP protocols for culture, identification, and antibiotic-sensitivity testing using 2 methods-disk diffusion (Kirby-Bauer test) and Etest (BioMérieux Inc). A subset of samples underwent detailed antimicrobial resistance testing. Of 639 samples collected from September 2016 to February 2018, 400 (62.6%) were culture-positive though 414 (64.8%) had microscopic evidence of gonorrhea. The mean age of the men from whom the samples were c...Continue Reading

References

Nov 11, 2009·Sexually Transmitted Diseases·Lillian B BrownIrving F Hoffman
Jun 30, 2010·Antimicrobial Agents and Chemotherapy·Stephanie A ChisholmCatherine A Ison
Sep 7, 2013·BMC Infectious Diseases·Martha TibebuAfework Kassu
Mar 14, 2014·Sexually Transmitted Diseases·Judith VandepitteDavid A Lewis
Jul 2, 2014·Clinical Microbiology Reviews·Magnus Unemo, William M Shafer
Jul 2, 2016·Infectious Diseases in Obstetrics and Gynecology·Philip A ChanErica J Hardy
Dec 3, 2016·Antimicrobial Resistance and Infection Control·Hsi LiuDavid Trees
May 27, 2017·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Alan R KatzJuval E Tomas
Oct 13, 2017·Sexually Transmitted Infections·Dissou AffolabiMichel Alary
Nov 14, 2017·Emerging Infectious Diseases·Brigitte LefebvreJean Longtin
Dec 15, 2017·Sexually Transmitted Diseases·Cornelis A RietmeijerMufuta Tshimanga
Mar 20, 2018·Emerging Infectious Diseases·Shao-Chun ChenXiang-Sheng Chen
Apr 27, 2018·MMWR. Morbidity and Mortality Weekly Report·Emily J WestonMark R Stenger
Mar 7, 2019·Frontiers in Immunology·Angela Lovett, Joseph A Duncan
Aug 7, 2019·Bulletin of the World Health Organization·Jane RowleyMelanie M Taylor

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Citations

Feb 18, 2021·Journal of Translational Medicine·Richard KwizeraDavid B Meya
May 14, 2021·Science Translational Medicine·Alexander Y TrickTza-Huei Wang
Jun 3, 2021·Tropical Medicine and Infectious Disease·Mark Tefero Kivumbi, Claire J Standley

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Software Mentioned

Etest
SAS
GASP
EGASP
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