Abstract
Aim
. Urinary tract infection (UTI) is considered one of the most common bacterial infections in women. The aim of this study was to investigate the types of uropathogens present, as well as the degree of antimicrobial drug resistance seen among premenopausal (n= 2748) and postmenopausal (n= 1705) women with uncomplicated UTI.Methods. Urinary samples (n= 4453) collected from women with UTI were analyzed in terms of uropathogens present. These were considered as positive if bacterial growth was ≥105colony forming units (CFUs)/mL. Susceptibility and resistance testing for commonly used antibiotics was subsequently assessed.Results. The most common uropathogens cultured from urine samples wereEscherichia coli(65.5%), followed byEnterococcus faecalis(12.2%),Klebsiella pneumoniae(4.7%), andProteus mirabilis(4.2%). The resistance to ampicillin exceeded 40%, independently of menopausal status. Of note, resistance to ciprofloxacin exceeded 25% among postmenopausal patients. Moreover, resistance of all uropathogens to commonly used antimicrobials was significantly higher in postmenopausal women.Conclusion. Due to the high resistance rate, ampicillin, ciprofloxacin, and the trimethoprim/sulfamethoxazole combination should be avoided in t...Continue Reading
References
Jun 5, 2001·The Journal of Antimicrobial Chemotherapy·K HryniewiczW Hryniewicz
Jun 19, 2004·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Thomas M HootonLindsay E Nicolle
Mar 11, 2005·The Journal of Urology·Tomas L Griebling
Jun 10, 2009·International Journal of Antimicrobial Agents·Gian Carlo SchitoAnna Marchese
Nov 27, 2009·Neurourology and Urodynamics·Bernard T HaylenUNKNOWN International Continence Society
Oct 18, 2011·International Journal of Antimicrobial Agents·Kurt G NaberFlorian M E Wagenlehner
Feb 4, 2014·Infectious Disease Clinics of North America·Betsy Foxman
Feb 27, 2014·JAMA : the Journal of the American Medical Association·Lona Mody, Manisha Juthani-Mehta
Jan 21, 2015·Nature Reviews. Urology·Samantha A WhitesideJeremy P Burton
Feb 7, 2015·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·A J StewardsonUNKNOWN SATURN WP1 and WP3 Study Groups
May 27, 2015·Maturitas·Dudley RobinsonLinda Cardozo
May 18, 2016·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·E StefaniukW Hryniewicz
May 29, 2016·Infection·Louise RossignolBruno Coignard
Sep 7, 2016·Urologia Internationalis·Jakhongir F AlidjanovFlorian M E Wagenlehner
Oct 6, 2016·Open Forum Infectious Diseases·Miwako KobayashiLauri A Hicks
Citations
Oct 4, 2019·Central European Journal of Public Health·Zorana DjordjevićSlobodan Janković
Aug 18, 2020·Neurourology and Urodynamics·Megan S BradleyMary F Ackenbom
Aug 5, 2020·Antimicrobial Agents and Chemotherapy·Ann E StapletonMonique Twynholm
Jul 28, 2019·Archives of Gynecology and Obstetrics·Sara WawrysiukPawel Miotla
Aug 6, 2020·Antibiotics·Răzvan-Cosmin PetcaCălin Bogdan Chibelean
Sep 13, 2018·Journal of Clinical Medicine·Pawel MiotlaTomasz Rechberger
Nov 3, 2020·International Journal of Microbiology·Dhifar Raa'd Al-Guranie, Sareaa Maseer Al-Mayahie
Jul 21, 2021·Current Microbiology·Ghada Hani Ali, Marwa A Yakout