PMID: 29769930Feb 5, 2015Paper

Antimicrobial resistance to Neisseria gonorrhoeae in Canada: 2009-2013

Canada Communicable Disease Report = Relevé Des Maladies Transmissibles Au Canada
I MartinM R Mulvey

Abstract

Gonorrhea is on the rise in Canada. Treatment has been complicated by the fact that Neisseria gonorrhoeae has acquired resistance to many antibiotics, including penicillin, tetracycline, erythromycin and ciprofloxacin. The emergence of isolates with decreased susceptibilities to the third generation cephalosporins and reports of treatment failures in Canada and around the world are cause for concern. To assess the resistance levels of common antibiotics to N. gonorrhoeae and to observe trends in resistance and/or decreased susceptibility to ciprofloxacin, third generation cephalosporins and azithromycin. Laboratory surveillance data for N. gonorrhoeae isolates submitted by provincial microbiology laboratories to the National Microbiology Laboratory (NML) from 2009-2013 were compared. Since 2009, there has been an overall rise in antibiotic-resistant N. gonorrhoeae. In 2013, 24.3% of the isolates were resistant to erythromycin, 18.9% were resistant to penicillin, 33.0% were resistant to tetracycline, and 29.3% were resistant to ciprofloxacin. The percentage of isolates with decreased susceptibility to ceftriaxone (≥0.125 mg/L) and/or cefixime (≥0.25 mg/L) was 3.9% in 2013. This number represents a decrease from 5.9% in 2012 and ...Continue Reading

Citations

Feb 2, 2017·Canada Communicable Disease Report = Relevé Des Maladies Transmissibles Au Canada·S HaM Gale-Rowe
Sep 23, 2020·The Cochrane Database of Systematic Reviews·Vimal Scott KapoorS Swaroop Vedula
May 18, 2018·Canada Communicable Disease Report = Relevé Des Maladies Transmissibles Au Canada·Y ChoudhriJ Aho
Oct 18, 2018·Frontiers in Microbiology·David SychanthaAnthony J Clarke
Jun 10, 2021·Global Pediatric Health·Samuel Bert Boadi-KusiAbena Mantebea Ateko

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