Antimicrobial-resistant bacterial diarrhea in rural western Kenya

The Journal of Infectious Diseases
R L ShapiroL Slutsker

Abstract

Bacterial diarrheal diseases cause substantial morbidity and mortality in sub-Saharan Africa, but data on the epidemiology and antimicrobial susceptibility patterns of enteric bacterial pathogens are limited. Between May 1997 and April 1998, a clinic-based surveillance for diarrheal disease was conducted in Asembo, a rural area in western Kenya. In total, 729 diarrheal specimens were collected, and 244 (33%) yielded >or=1 bacterial pathogen, as determined by standard culture techniques; 107 (44%) Shigella isolates, 73 (30%) Campylobacter isolates, 45 (18%) Vibrio cholerae O1 isolates, and 33 (14%) Salmonella isolates were identified. Shigella dysenteriae type 1 accounted for 22 (21%) of the Shigella isolates. Among 112 patients empirically treated with an antimicrobial agent and whose stool specimens yielded isolates on which resistance testing was done, 57 (51%) had isolates that were not susceptible to their antimicrobial treatment. Empiric treatment strategies for diarrheal disease in western Kenya need to be reevaluated, to improve clinical care.

Citations

Jul 14, 2006·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·John T BrooksLaurence Slutsker
Jul 14, 2006·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Theodore S SteinerRichard L Guerrant
Sep 25, 2004·Antimicrobial Agents and Chemotherapy·Roberto CabreraJordi Vila
May 1, 2013·The American Journal of Tropical Medicine and Hygiene·Dilruba NasrinKaren L Kotloff
Feb 27, 2014·BMC Infectious Diseases·Frederique RandrianirinaAntoine Talarmin
Dec 12, 2012·Transactions of the Royal Society of Tropical Medicine and Hygiene·Brett E SwierczewskiEdwin V Oaks
Jun 1, 2014·The Journal of Antimicrobial Chemotherapy·Stije J LeopoldConstance Schultsz
Aug 27, 2005·The Lancet Infectious Diseases·Iruka N OkekeRamanan Laxminarayan
Mar 26, 2003·The Journal of Veterinary Medical Science·Pawin Padungton, John B Kaneene
Feb 27, 2015·Antimicrobial Resistance and Infection Control·Sylvia OmuloDouglas R Call
Sep 10, 2004·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·S D PutnamR W Frenck
Jul 29, 2005·The Lancet Infectious Diseases·Iruka N OkekeKeith P Klugman
Jan 19, 2018·Therapeutic Advances in Infectious Disease·Margaret MokomaneDavid M Goldfarb
Jan 16, 2020·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·Iqbal NisaWaheed Ullah

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