Antimicrobial-resistant Shigella infections from Iran: an overlooked problem?

The Journal of Antimicrobial Chemotherapy
Mercedeh TajbakhshRene S Hendriksen

Abstract

In this study, we wanted to assess the level of antimicrobial resistance, the presence of genes encoding resistance to cephalosporins and plasmid-mediated quinolone resistance (PMQR), and genetic relatedness among Shigella isolates obtained from Iranian patients. A total of 44 Shigella isolates were collected from Iranian patients admitted to Milad Hospital, Tehran, Iran, during 2008-10. Of these, 37 were serotyped and characterized by MIC determination. A subset of eight suspected extended-spectrum β-lactamase (ESBL) producers (six Shigella sonnei phase II and two Shigella flexneri type 1b) were examined for the presence of genes encoding cephalosporin resistance. The presence of PMQR was assessed in one S. flexneri isolate exhibiting low-level resistance to ciprofloxacin and susceptibility to nalidixic acid. PFGE was performed on 25 S. sonnei phase II isolates. Of the isolates, 25 (68%) were S. sonnei phase II, with 5 (14%) S. flexneri, 5 (14%) Shigella dysenteriae type 2, and 2 (5%) Shigella boydii type 2. Resistance to at least threeclasses of antimicrobials was detected in all species. The presence of bla(CTX-M-15) and the AmpC β-lactamase producer bla(CMY-2) was confirmed in five and one S. sonnei phase II isolates, respe...Continue Reading

References

Mar 1, 1991·Reviews of Infectious Diseases·M L Bennish, B J Wojtyniak
Oct 1, 1988·Annals of Tropical Medicine and Parasitology·J Nikkah, A Mehr-Movahead
Sep 30, 2003·Scandinavian Journal of Infectious Diseases·Ziya Cibali AcikgozSohret Gamberzade
Nov 5, 2004·Journal of Veterinary Medicine. B, Infectious Diseases and Veterinary Public Health·F M Aarestrup
Jan 28, 2005·Antimicrobial Agents and Chemotherapy·Mami HataKenji Sakae
Feb 1, 2007·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·V VasilevD Cohen
May 26, 2007·The Journal of Infection·Charles FeldmanUNKNOWN International Pneumococcal Study Group
Oct 24, 2007·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·S K Niyogi
Dec 25, 2007·The Korean journal of laboratory medicine·Seong Jin HongSuk Hoon Jung
Feb 5, 2008·International Journal of Antimicrobial Agents·M RapoportM Galas
Jan 13, 2009·Indian Journal of Pathology & Microbiology·Mohammad Taghi Hghi AshtianiLeila Kashi
Mar 20, 2009·The Journal of Antimicrobial Chemotherapy·Xiao-Ying PuYang-Ming Gu
Jun 6, 2009·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Peter CollignonFrank M Aarestrup
Nov 12, 2010·Journal of Clinical Microbiology·Shengli XiaRene S Hendriksen
Dec 15, 2010·Diagnostic Microbiology and Infectious Disease·Rong ZhangXin-you Xie
Jan 12, 2011·Antimicrobial Agents and Chemotherapy·Jason P FolsterJean M Whichard
Feb 1, 2011·International Journal of Antimicrobial Agents·David M LivermoreMarina Warner

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Citations

Oct 2, 2013·Proceedings of the National Academy of Sciences of the United States of America·Kathryn E HoltStephen Baker
Mar 20, 2013·Indian Journal of Medical Microbiology·S OommenP Jose Paul
Aug 12, 2014·Current Tropical Medicine Reports·Mussaret Bano Zaidi, Teresa Estrada-García
May 3, 2014·Journal of Medical Microbiology·Santanu GhoshThandavarayan Ramamurthy
May 23, 2015·International Journal of Medical Microbiology : IJMM·Angela LluqueJoaquim Ruiz
Jun 3, 2015·Jundishapur Journal of Microbiology·Mojtaba MemarianiSeyyed Khalil Shokouhi Mostafavi
Dec 9, 2014·International Journal of Food Microbiology·Ashraf M Ahmed, Tadashi Shimamoto
Jun 13, 2015·PLoS Neglected Tropical Diseases·Corinne N ThompsonStephen Baker
Jan 1, 2013·Antimicrobial Agents and Chemotherapy·Maria Sjölund KarlssonJean M Whichard
Dec 24, 2015·Microbial Genomics·Hao Chung TheStephen Baker
Apr 11, 2018·Infection & chemotherapy·Sajjad ZamanlouYounes Khalili
May 14, 2017·Annals of Clinical Microbiology and Antimicrobials·Ping ShenYonghong Xiao
Feb 3, 2018·Journal of Food Science and Technology·Khashayar Shahin, Majid Bouzari
Apr 1, 2020·Acta Microbiologica Et Immunologica Hungarica·Fatima Bachir HalimehJean-Marc Rolain

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