Abstract
To measure the impact of an antimicrobial stewardship (AMS) program on the use of antibiotics for surgical prophylaxis at acute care hospitals in Egypt. This was a before-and-after intervention study conducted in 5 tertiary, acute-care surgical hospitals. The baseline, intervention, and follow-up periods were 3, 6, and 3 months, respectively. The impact of the intervention was measured by preintervention and postintervention surveys for surgical patients with clean and clean-contaminated wounds. Information was collected on demographic characteristics and antibiotic use. The intervention focused mainly on educating surgical staff on the optimal timing and duration of antibiotics used for surgical prophylaxis. Only 3 hospitals identified a surgeon to audit antibiotic surgical prescriptions. The primary outcome measures were the percentages of surgical patients receiving optimal timing and duration of surgical prophylaxis. Data were collected for 745 patients before the intervention and for 558 patients after the intervention. The optimal timing of the first dose improved significantly in 3 hospitals, increasing from 6.7% to 38.7% (P < .01), from 2.6% to 15.2% (P < .01), and from 0% to 11% (P < .01). All hospitals showed a signif...Continue Reading
References
Jun 28, 2000·Circulation·S HarbarthY Carmeli
Jul 6, 2000·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·R E Istúriz, C Carbon
Aug 7, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·J P Burke
Oct 20, 2005·The Journal of Antimicrobial Chemotherapy·Marjo E E van KasterenInge C Gyssens
Jul 3, 2008·The Journal of Antimicrobial Chemotherapy·Michael A BorgUNKNOWN ARMed Project Group
Aug 29, 2009·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Bernard C CaminsHenry M Blumberg
Sep 17, 2009·Journal of Infection in Developing Countries·Ozlem TungerHakan Borand
Dec 23, 2009·International Journal of Surgery·Hedef OzgunMujgan Aydemir
May 24, 2012·The Breast Journal·Muhammad S SajidRicardo Bonomi
Citations
Apr 20, 2016·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·Ibrahim FathiMarwa Ramadan
Jul 28, 2016·Journal of Infection and Public Health·Humberto G GarcellRamon N Alfonso Serrano
Nov 10, 2016·Surgical Infections·Massimo SartelliJohn E Mazuski
Mar 8, 2019·PloS One·Usman AbubakarAdebiyi Gbadebo Adesiyun
Jul 29, 2018·International Journal of Clinical Pharmacy·U AbubakarA G Adesiyun
Nov 18, 2020·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Elisavet ChorafaUNKNOWN Preventing Hospital-Acquired Infections in Greece (PHiG) investigators
Jan 14, 2021·Antimicrobial Resistance and Infection Control·Katherine Romero ViamonteAna Martín-Suárez
Jan 15, 2021·Scientific Reports·Hessa Saleh AlshehhiAzzan Alsaadi
Jul 28, 2020·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Shaheen MehtarJoseph S Solomkin
Feb 27, 2021·International Journal of General Medicine·Julius C MwitaBrian Godman
Feb 16, 2020·The Lancet Infectious Diseases·Ramanan LaxminarayanYong-Guan Zhu
Jul 6, 2021·JAC-antimicrobial Resistance·Lesley CooperR Andrew Seaton
Jul 3, 2021·Life·Brian GodmanR Andrew Seaton
Jul 22, 2021·Pharmacy : Journal of Pharmacy, Education and Practice·Frances KerrDiane Ashiru-Oredope
Jul 18, 2017·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·J A CoxG Levy Hara