Antimicrobial stewardship to optimize the use of antimicrobials for surgical prophylaxis in Egypt: A multicenter pilot intervention study

American Journal of Infection Control
Tamer SaiedMaha Talaat

Abstract

To measure the impact of an antimicrobial stewardship (AMS) program on the use of antibiotics for surgical prophylaxis at acute care hospitals in Egypt. This was a before-and-after intervention study conducted in 5 tertiary, acute-care surgical hospitals. The baseline, intervention, and follow-up periods were 3, 6, and 3 months, respectively. The impact of the intervention was measured by preintervention and postintervention surveys for surgical patients with clean and clean-contaminated wounds. Information was collected on demographic characteristics and antibiotic use. The intervention focused mainly on educating surgical staff on the optimal timing and duration of antibiotics used for surgical prophylaxis. Only 3 hospitals identified a surgeon to audit antibiotic surgical prescriptions. The primary outcome measures were the percentages of surgical patients receiving optimal timing and duration of surgical prophylaxis. Data were collected for 745 patients before the intervention and for 558 patients after the intervention. The optimal timing of the first dose improved significantly in 3 hospitals, increasing from 6.7% to 38.7% (P < .01), from 2.6% to 15.2% (P < .01), and from 0% to 11% (P < .01). All hospitals showed a signif...Continue Reading

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Citations

Jul 28, 2016·Journal of Infection and Public Health·Humberto G GarcellRamon N Alfonso Serrano
Nov 10, 2016·Surgical Infections·Massimo SartelliJohn E Mazuski
Jul 29, 2018·International Journal of Clinical Pharmacy·U AbubakarA G Adesiyun
Nov 18, 2020·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Elisavet ChorafaUNKNOWN Preventing Hospital-Acquired Infections in Greece (PHiG) investigators
Jul 28, 2020·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Shaheen MehtarJoseph S Solomkin
Feb 16, 2020·The Lancet Infectious Diseases·Ramanan LaxminarayanYong-Guan Zhu
Jul 22, 2021·Pharmacy : Journal of Pharmacy, Education and Practice·Frances KerrDiane Ashiru-Oredope
Jul 18, 2017·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·J A CoxG Levy Hara

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An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

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