Antimicrobial susceptibility of Neisseria gonorrhoeae strains isolated in 2004-2006 in Bangui, Central African Republic; Yaoundé, Cameroon; Antananarivo, Madagascar; and Ho Chi Minh Ville and Nha Trang, Vietnam

Sexually Transmitted Diseases
Van CaoA Talarmin

Abstract

To investigate the in vitro antimicrobial susceptibility of Neisseria gonorrhoeae strains isolated in 2004 and 2005 in Bangui, Central African Republic; Yaoundé, Cameroon; Antananarivo, Madagascar; and Ho Chi Minh Ville and Nha Trang, Vietnam. Antimicrobial susceptibility testing was performed by both disk diffusion and agar dilution methods according to Clinical and Laboratory Standards Institute (CLSI) recommendations. Minimum inhibitory concentrations (MICs) to 5 antimicrobials (penicillin G, ceftriaxone, ciprofloxacin, spectinomycin, and tetracycline) were determined when feasible. Penicillinase-producing N. gonorrhoeae (PPNG) was analyzed by the paper acidometric method (nitrocefin test). Thirty N. gonorrhoeae isolates from Bangui could be studied, 79 from Yaoundé, 126 from Antananarivo, 56 from Nha Trang, and 126 from Ho Chi Minh Ville in 2004 and 2005. Unfortunately, because of problems of electricity supply, no strains could be recovered for the determination of MICs in Yaoundé, and only 68 strains could be tested in Antananarivo and 121 in Ho Chi Minh Ville. Patterns of resistance were similar in Antananarivo, Bangui, and Yaoundé but different from those observed in Vietnam. Ciprofloxacin was highly effective in Africa...Continue Reading

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Citations

Mar 3, 2011·Current Infectious Disease Reports·Robert D KirkcaldyDeborah Dowell
Nov 28, 2013·Sexually Transmitted Infections·Francis J NdowaMarie Christine Fonkoua
Sep 7, 2013·BMC Infectious Diseases·Martha TibebuAfework Kassu
Oct 12, 2010·Journal of Global Infectious Diseases·Manju Bala, Seema Sood
Jun 1, 2014·The Journal of Antimicrobial Chemotherapy·Stije J LeopoldConstance Schultsz
Jun 16, 2009·Journal of the European Academy of Dermatology and Venereology : JEADV·J Lis-Tønder, Z Cybulski
Sep 21, 2018·Sexually Transmitted Diseases·Carolle Y Tayimetha, Magnus Unemo
Nov 11, 2009·Sexually Transmitted Diseases·Lillian B BrownIrving F Hoffman
Mar 17, 2009·Expert Opinion on Pharmacotherapy·Pennan M Barry, Jeffrey D Klausner
Dec 13, 2017·Journal of Medical Microbiology·Sangeeta V KulkarniSheela V Godbole
Sep 9, 2009·Expert Review of Anti-infective Therapy·John W TapsallMagnus Unemo

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