Aug 13, 2013

Antimicrobial therapy for chronic bacterial prostatitis

The Cochrane Database of Systematic Reviews
Gianpaolo PerlettiVittorio Magri

Abstract

Chronic bacterial prostatitis (CBP) is frequently diagnosed in men of fertile age, and is characterized by a disabling array of symptoms, including pain in the pelvic area (for example, perineum, testicles), voiding symptoms (increased frequency and urgency, also at night; pain or discomfort at micturition), and sexual dysfunction. Cure of CBP can be attempted by long-term therapy with antibacterial agents, but relapses are frequent. Few antibacterial agents are able to distribute to the prostatic tissue and achieve sufficient concentrations at the site of infection. These agents include fluoroquinolones, macrolides, tetracyclines and trimethoprim. After the introduction of fluoroquinolones into clinical practice, a number of studies have been performed to optimize the antimicrobial treatment of CBP, and to improve eradication rates and symptom relief. To assess and compare the efficacy and harm of antimicrobial treatments for chronic bacterial prostatitis. We searched the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE (PubMed), EMBASE, other national or international databases and abstracts from conference proceedings on 8 August 2012. We included all randomized controlled comparisons of one antimicrobial ag...Continue Reading

Mentioned in this Paper

Tetracycline Antibiotics
Fertility
Azithromycin
Urination
Chlamydia Infections
Fluoroquinolone antiinfectives, ophthalmologic
Tetracyclines
Doxycycline
beta-Lactams
Chlamydial Pneumonia

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