Antimicrobial therapy for intra-abdominal infections: guidelines from the Infectious Disease Advisory Board (IDAB)

Acta chirurgica Belgica
P F LaterreIDAB

Abstract

Intra-abdominal infection is a common cause of severe sepsis in a hospital setting and remains associated with a significant morbidity, mortality and resource use. Early adequate surgery or drainage remain the cornerstones of intra-abdominal infection management and impact on patients outcome. Concomitant early and adequate empiric antimicrobial therapy further influences patients morbidity and mortality. Multiple empirical regimens have been proposed in this setting, but rarely supported by well designed, randomized-controlled studies. The current manuscript summarizes the recommendations of the Infection Disease Advisory Board on the management of intra-abdominal infections. Empiric antimicrobial therapy for the most common causes of abdominal infections is proposed. In addition, particular attention has been paid on antibiotic treatment duration.

Citations

Apr 22, 2011·Expert Opinion on Pharmacotherapy·Itzhak Brook
Nov 28, 2007·Expert Review of Anti-infective Therapy·Itzhak Brook
Mar 18, 2016·Intensive Care Medicine·P MontraversJ De Waele
Aug 6, 2009·Journal of Chemotherapy·S Esposito, E Petta

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