Antimicrobial treatment of intra-abdominal infections

Digestive Diseases
R ElsakrE C Oldfield

Abstract

There have been several recent changes that influence the management of intra-abdominal infections. These changes include important developments in antibiotic resistance such as increases in pneumococcal resistance, emergence of multi-drug-resistant enterococcal isolates, and decreasing sensitivity of anaerobes and gram-negative rods. In addition there are new antibiotics such as piperacillin/tazobactam, and new antibiotic dosing regimens such as single daily dosing of aminoglycosides. In this article, we will review the therapeutic approach to intra-abdominal infections with special emphasis on the various forms of peritonitis, cholecystitis, cholangitis, and diverticulitis. Several new concepts about the treatment of enterococcus, the management of bacterial and fungal peritonitis, and the prevention of spontaneous bacterial peritonitis will also be reviewed. Specific recommendations for the management of the different infections including antibiotic doses and costs will be provided. Finally the role of invasive procedures in the management of some of the infections will be explored.

Citations

Feb 9, 2010·International Journal of Colorectal Disease·Christine Schug-PassFerdinand Köckerling
Oct 19, 2002·International Journal of Antimicrobial Agents·Albert E YellinUNKNOWN 004 Intra-abdominal Infection Study Group
Jan 25, 2003·Surgical Infections·John E MazuskiUNKNOWN Therapeutic Agents Committee of the Surgical Infections Society
Feb 20, 2009·Surgical Infections·Matthew C Byrnes, John E Mazuski
Apr 28, 2007·International Journal of Surgery·Narcisco S NavarroUNKNOWN Oasis II Study Team
Apr 22, 2006·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Arturo S Dela PenaUNKNOWN Optimizing Intra-Abdominal Surgery with Invanz (OASIS)-I Study Group
Dec 28, 2006·Scandinavian Journal of Gastroenterology·Fredrik HjernClaes Johansson
Nov 2, 2014·United European Gastroenterology Journal·Rosario CuomoBruno Annibale
Aug 19, 2003·Drugs·Monique CurranCaroline Perry

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Antimicrobial Resistance

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.

Allergy & Infectious Diseases

Allergies result from the hyperreactivity of the immune system to some environmental substance and can be life-threatening. Infectious diseases are caused by organisms including bacteria, viruses, fungi and parasites. They can be transmitted different ways, such as person-to-person. Here is the latest research on allergy and infectious diseases.

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