PMID: 9547521Apr 21, 1998Paper

Antimycobacterial activity of 3'- and 4'-fluorothiobenzanilides

Die Pharmazie
K WaisserV Horák

Abstract

On the basis of a preliminary study of the antimycobacterial activity of thiobenzanilides, a group of 3'-fluoro- and 4'-fluorothiobenzanilides has been synthesized and tested against Mycobacterium tuberculosis, M. kansasii, M. avium and M. fortuitum. The results of this study demonstrate that electron withdrawing groups increase the activity of thiobenzanilides and fluoro benzothioanilides against atypical strains which is higher then that of INH.

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Antifungals (ASM)

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