Abstract
Lipopeptide biosurfactants constitute one of the most promising groups of compounds for the treatment and prevention of fungal diseases in plants. Bacillus subtilis strain EA-CB0015 produces iturin A, fengycin C and surfactin and it has been proven useful for the treatment of black Sigatoka disease in banana plants, an important pathology caused by the fungus Mycosphaerella fijiensis (Morelet). We have found that B. subtilis EA-CB0015 cell free supernatants and purified fractions inhibit M. fijiensis cellular growth. The effect of the purified lipopeptides mentioned above on fungal growth has been also evaluated, observing that iturin A and fengycin C inhibit mycelial growth and ascospore germination, whereas surfactin is not effective. On the hypothesis that the antifungal action of the lipopeptides is associated to their incorporation into biological membranes, ultimately leading to membrane permeabilization, a detailed biophysical study on the interaction of a new isoform of fengycin C with model dipalmitoyphosphatidylcholine (DPPC) membranes has been carried out. Differential scanning calorimetry shows that fengycin C alters the thermotropic phase transitions of DPPC, and is laterally segregated in the fluid bilayer forming...Continue Reading
Citations
Oct 31, 2018·Applied Microbiology and Biotechnology·M Elisa FaitMario C N Saparrat
Mar 14, 2018·Scientific Reports·Yu CaoYanfei Cai
Feb 14, 2020·Microorganisms·Marwa M Abdel-AzizTamer M Emam
Nov 7, 2019·Scientific Reports·Anastasiia A ZakharovaOlga S Ostroumova
Aug 9, 2020·Frontiers in Genetics·Zheyuan ZhuDi Peng
Jul 8, 2017·Applied Microbiology and Biotechnology·Haobin ZhaoMingliang Jin
May 18, 2019·The Journal of Membrane Biology·Daniel BallezaMiguel J Beltrán García
Nov 7, 2019·Frontiers in Microbiology·Hélène DesmytterePhilippe Jacques
Oct 16, 2019·The Journal of Membrane Biology·Elisabeth MantilTyler J Avis
May 24, 2020·Plants·Aurélien L FurlanSébastien Buchoux
Feb 11, 2020·Frontiers in Microbiology·Daniela B MedeotEdgardo Jofré
Dec 23, 2020·Journal of Hazardous Materials·Femina Carolin CP Tsopbou Ngueagni
Jan 15, 2019·Biochimica Et Biophysica Acta. Biomembranes·Elisabeth MantilTyler J Avis
Jun 13, 2021·Journal of Biotechnology·Nicolas SchlosserLars Regestein
Sep 9, 2017·Langmuir : the ACS Journal of Surfaces and Colloids·Jonathan R CoronelAntonio Ortiz
Oct 31, 2021·Journal of Applied Microbiology·Meichun ChenYujing Zhu