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Antinociception occurs with a reversal in alpha 2-adrenoceptor regulation of TNF production by peripheral monocytes/macrophages from pro- to anti-inflammatory

European Journal of Pharmacology

Jul 7, 2008

Reeteka SudTracey A Ignatowski

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Abstract

Tumor necrosis factor-alpha (TNF) plays a role in neuropathic pain. During neuropathic pain development in the chronic constriction injury model, elevated TNF levels in the brain occur in association with enhanced alpha 2-adrenoceptor inhibition of norepinephrine release. alpha 2-Adreno...read more

Mentioned in this Paper

Salicylhydroxamic acid
Amitriptyline
Peripheral Nerves
GTP-Binding Proteins
Regulation of Tumor Necrosis Factor Production
NOVA2 gene
Cerebral Ventricles
Nervousness
Tumor Necrosis Factor Production
Malignant Neoplasm of Cerebral Ventricles
26
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Antinociception occurs with a reversal in alpha 2-adrenoceptor regulation of TNF production by peripheral monocytes/macrophages from pro- to anti-inflammatory

European Journal of Pharmacology

Jul 7, 2008

Reeteka SudTracey A Ignatowski

PMID: 18514187

DOI: 10.1016/j.ejphar.2008.04.043

Abstract

Tumor necrosis factor-alpha (TNF) plays a role in neuropathic pain. During neuropathic pain development in the chronic constriction injury model, elevated TNF levels in the brain occur in association with enhanced alpha 2-adrenoceptor inhibition of norepinephrine release. alpha 2-Adreno...read more

Mentioned in this Paper

Salicylhydroxamic acid
Amitriptyline
Peripheral Nerves
GTP-Binding Proteins
Regulation of Tumor Necrosis Factor Production
26
1

Similar Papers Found In These Feeds

Related Papers

Paper Details
References
  • References59
  • Citations9
12345...
  • References59
  • Citations9
1

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