PMID: 6982285Oct 1, 1982Paper

Antinuclear antibody-negative systemic lupus erythematosus-how common?

Journal of Clinical Pathology
K C McHardyJ Rennie

Abstract

A review of five years' DNA-binding antibody results in a routine service laboratory revealed 38 patients who had high DNA-binding capacity (DNA-bc) but no antinuclear antibodies (ANA). On retrospective case note analysis, 22 patients (58%) were thought to have systemic lupus erythematosus (SLE), although only six (16%) fulfilled the preliminary classification criteria of the American Rheumatism Association (ARA). Our findings indicate that ANA-negative SLE is commoner than generally realised and lead us to recommended the measurement of DNA-bc in every case where clinically appropriate.

References

Jan 1, 1978·The American Journal of Medicine·W J Fessel
Oct 1, 1975·Annals of the Rheumatic Diseases·T Gibson, A R Myers
Nov 11, 1972·British Medical Journal·R BennettP J Holt
Apr 1, 1974·American Journal of Clinical Pathology·B A Bartholomew
Jul 14, 1973·British Medical Journal·P DavisG R Hughes
May 1, 1971·Annals of the Rheumatic Diseases·G R HughesC L Christian
Jul 1, 1968·Medicine·R T Johnson, E P Richardson
Sep 25, 1969·The New England Journal of Medicine·T PincusN Talal
Jan 1, 1981·Journal of the American Academy of Dermatology·T T Provost, M Reichlin
Dec 1, 1952·A.M.A. Archives of Internal Medicine·M A SHEARN, B PIROFSKY
Oct 12, 1964·JAMA : the Journal of the American Medical Association·E L DUBOIS, D L TUFFANELLI

❮ Previous
Next ❯

Citations

Aug 1, 1985·Annals of the Rheumatic Diseases·K C McHardyC H Horne
Jul 26, 2012·ISRN Hematology·P K SasidharanK G Sajeeth Kumar
Apr 22, 2004·QJM : Monthly Journal of the Association of Physicians·L S CrossS A Misbah
Sep 18, 2009·Annals of the New York Academy of Sciences·Cristiano AlessandriGuido Valesini
Mar 10, 2009·The Korean Journal of Internal Medicine·Hyoun Ah KimChang Hee Suh
Oct 14, 2017·Rheumatology·Caroline GordonUNKNOWN British Society for Rheumatology Standards, Audit and Guidelines Working Group
May 26, 2017·Arthritis Care & Research·Nicolai LeuchtenUNKNOWN Systemic Lupus Erythematosus Classification Criteria Steering Committee
Feb 12, 2019·Journal of Proteome Research·Frida TorellJohan Trygg

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.