Antioxidant activity, cytotoxic activity and metabolic profiling of juices obtained from saffron (Crocus sativus L.) floral by-products

Food Chemistry
Carlo I G TuberosoCosimo Pizza

Abstract

Juices obtained from cold-pressed saffron (Crocus sativus L.) floral by-products were evaluated as a potential source of compounds with antioxidant and cytotoxic activities. Floral by-products were split in two batches for extraction 24 and 48h after flower harvesting, respectively. The in vitro anti-oxidant activity of these extracts was tested using the FRAP and DPPH assays, and two biological models of lipid oxidation (activity in preventing cholesterol degradation and protection against Cu(2+)-mediated degradation of the liposomal unsaturated fatty acids). The cytotoxic activity was evaluated using the MTT assay. The results show that extracts obtained 48h post-harvest contained higher levels of total polar phenols and had the highest antioxidant activity in all of the performed assays. The LC-DAD and LC-ESI-(HR)MS(n) metabolic profiles showed high levels of kaempferol derivatives and anthocyanins. This study suggests that juices from saffron floral by-products could potentially be used to develop new products for the food and health industry.

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Citations

Jun 16, 2018·Nanomedicine·Hardi JogiRakesh Kumar Tekade
Feb 28, 2018·Phytochemical Analysis : PCA·Erica CusanoMoschos G Polissiou
Aug 7, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Natalia Moratalla-LópezGonzalo L Alonso
May 16, 2019·Natural Product Research·Samareh BabaeiMehrdad Behmanesh
Jan 30, 2020·Food Science & Nutrition·Hamed Kaveh, Safieh Vatandoost
Aug 27, 2021·Journal of Ethnopharmacology·Bingcong XingQingsong Shao

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