Antioxidant activity, inhibition of nitric oxide overproduction, and in vitro antiproliferative effect of maple sap and syrup from Acer saccharum

Journal of Medicinal Food
Jean LegaultAndré Pichette

Abstract

Antioxidant activity, inhibition of nitric oxide (NO) overproduction, and antiproliferative effect of ethyl acetate extracts of maple sap and syrup from 30 producers were evaluated in regard to the period of harvest in three different regions of Québec, Canada. Oxygen radical absorbance capacity (ORAC) values of maple sap and syrup extracts are, respectively, 12 +/- 6 and 15 +/- 5 micromol of Trolox equivalents (TE)/mg. The antioxidant activity was also confirmed by a cell-based assay. The period of harvest has no statistically significant incidence on the antioxidant activity of both extracts. The antioxidant activity of pure maple syrup was also determined using the ORAC assay. Results indicate that the ORAC value of pure maple syrup (8 +/- 2 micromol of TE/mL) is lower than the ORAC value of blueberry juice (24 +/- 1 micromol of TE/mL) but comparable to the ORAC values of strawberry (10.7 +/- 0.4 micromol of TE/mL) and orange (10.8 +/- 0.5 micromol of TE/mL) juices. Maple sap and syrup extracts showed to significantly inhibit lipopolysaccharide-induced NO overproduction in RAW264.7 murine macrophages. Maple syrup extract was significantly more active than maple sap extract, suggesting that the transformation of maple sap int...Continue Reading

References

Oct 4, 2000·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·P A Brennan
Mar 21, 2002·The Lancet Oncology·P K Lala, C Chakraborty
Jan 29, 2003·The Journal of Nutritional Biochemistry·Kelly E. HeimDennis J. Bobilya
Aug 19, 2003·Archives of Biochemistry and Biophysics·Hiroshi OhshimaTomohiro Sawa
Mar 24, 2004·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·P Vitaglione, V Fogliano
Jan 11, 2005·The American Journal of Clinical Nutrition·Gary Williamson, Claudine Manach
Jan 20, 2006·Seminars in Cancer Biology·Michal Baniyash
Mar 3, 2006·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Barrett J Rollins
Mar 4, 2006·CA: a Cancer Journal for Clinicians·David Schottenfeld, Jennifer Beebe-Dimmer
Aug 22, 2006·Biochemical Pharmacology·Irfan RahmanPaul A Kirkham

❮ Previous
Next ❯

Citations

Dec 8, 2011·Bioscience, Biotechnology, and Biochemistry·Yuki WatanabeKeiko Abe
Sep 4, 2015·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·Cassandra L A HawcoDonald F Weaver
Jul 2, 2014·Journal of Agricultural and Food Chemistry·Yan ZhangNavindra P Seeram
Jan 11, 2014·Plant Foods for Human Nutrition·Amritpal S SinghPraveen K Saxena
Apr 14, 2016·Journal of Agricultural and Food Chemistry·Catherine AaronMartine Therrien
Dec 10, 2014·Journal of Medicinal Food·Pragati P NaharNavindra P Seeram
May 3, 2016·Journal of Ethnopharmacology·Wu BiPeigen Xiao
Sep 11, 2016·Journal of Agricultural and Food Chemistry·Jiadong SunDavid C Rowley
Jan 8, 2020·International Journal of Molecular Sciences·Audrey BélangerRoxane Pouliot
Feb 22, 2021·Functional & Integrative Genomics·Xiaoyu LuSongling Fu
Jun 29, 2021·Journal of Food Biochemistry·Mohamed Fawzy RamadanMohamed A Farag
Jul 3, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Héloïse CôtéJean Legault
Apr 22, 2016·Journal of Agricultural and Food Chemistry·Yongqiang LiuNavindra P Seeram
Aug 21, 2013·Bioorganic & Medicinal Chemistry Letters·Kasiviswanadharaju PericherlaAnil Kumar

❮ Previous
Next ❯

Methods Mentioned

BETA
Assay

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.