Antioxidant Activity/Capacity Measurement. 3. Reactive Oxygen and Nitrogen Species (ROS/RNS) Scavenging Assays, Oxidative Stress Biomarkers, and Chromatographic/Chemometric Assays

Journal of Agricultural and Food Chemistry
Reşat ApakEsra Capanoglu

Abstract

There are many studies in which the antioxidant potential of different foods have been analyzed. However, there are still conflicting results and lack of information as a result of unstandardized assay techniques and differences between the principles of the methods applied. The measurement of antioxidant activity, especially in the case of mixtures, multifunctional or complex multiphase systems, cannot be evaluated satisfactorily using a simple antioxidant test due to the many variables influencing the results. In the literature, there are many antioxidant assays that are used to measure the total antioxidant activity/capacity of food materials. In this review, reactive oxygen and nitrogen species (ROS/RNS) scavenging assays are evaluated with respect to their mechanism, advantages, disadvantages, and potential use in food systems. On the other hand, in vivo antioxidant activity (AOA) assays including oxidative stress biomarkers and cellular-based assays are covered within the scope of this review. Finally, chromatographic and chemometric assays are reviewed, focusing on their benefits especially with respect to their time saving, cost-effective, and sensitive nature.

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Citations

Sep 30, 2016·Journal of Agricultural and Food Chemistry·Mengmeng ZhangHui Wu
Apr 14, 2017·Journal of Agricultural and Food Chemistry·Amrita ChaudharyJyotirmoy Chatterjee
Dec 27, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Rui GengYixi Xie
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Dec 10, 2020·Evidence-based Complementary and Alternative Medicine : ECAM·Najlaa BassalatNidal Jaradat
Feb 23, 2021·Critical Reviews in Food Science and Nutrition·Xuan ChenZeyuan Deng
May 17, 2021·Food Research International·Yang YiHong-Xun Wang
Apr 17, 2018·The Journal of Organic Chemistry·Yohei OkadaHidehiro Kamiya
Mar 28, 2019·Organic Letters·Kaii NakayamaYohei Okada
Jul 2, 2019·Journal of Agricultural and Food Chemistry·Reşat Apak
Oct 27, 2021·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Xinyue GuoJilin Tang

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