PMID: 11906113Mar 22, 2002Paper

Antioxidant and anti-inflammatory activities of methanol extract of Phellinus rimosus (Berk) Pilat

Indian Journal of Experimental Biology
T A Ajith, Kainoor Krishnankutty Janardhanan

Abstract

The methanolic extract of a macrofungus, P. rimosus possessed significant in vitro superoxide anion, hydroxyl radical and nitric oxide scavenging and lipid peroxidation inhibiting activities. The anti-inflammatory activity of the extract was evaluated in carrageenan and dextran induced acute and formalin induced chronic inflammatory models in mice. The extract showed remarkable anti-inflammatory activity in both models, comparable to the standard reference drug diclofenac. The results suggest that the anti-inflammatory activity of the methanol extract of P. rimosus is possibly attributed to it's free radical scavenging properties. The findings also reveal the potential therapeutic value of P.rimosus extract as an antiinflammatory agent.

Related Concepts

Related Feeds

Anti-inflammatory Treatments

A drug or substance that reduces inflammation (redness, swelling, and pain) in the body. Anti-inflammatory agents block certain substances in the body that cause inflammation and swelling. Discover the latest research on anti-inflammatory treatments here

Related Papers

Journal of Ethnopharmacology
T A Ajith, Kainoor Krishnankutty Janardhanan
Journal of Experimental Therapeutics & Oncology
Thekkuttuparambil A Ajith, Kainoor Krishnankutty Janardhanan
Environmental Toxicology and Pharmacology
Kuttikkadan A RonyKainoor Krishnankutty Janardhanan
Journal of Experimental & Clinical Cancer Research : CR
T A AjithKainoor Krishnankutty Janardhanan
© 2022 Meta ULC. All rights reserved