Antioxidant, anti-inflammatory activities and acute toxicity of the polyherbal formulation: Romix®

Pharmaceutical Biology
Iskender InceN Ulku Karabay Yavasoglu

Abstract

Polyherbal formulations containing different plants are used for the treatment of various diseases. Romix® powder is a polyherbal formulation consisting of 14 traditionally used herbs and is used as a food supplement. There is no information about pharmaceutical activities of Romix®. This study determined the total phenolic and total flavonoid content, and investigated the antioxidant and anti-inflammatory activities and acute toxicity of Romix®. The total phenolics in the extracts were determined colorimetrically by using the Folin-Ciocalteu reagent. The total flavonoid content of the extracts was evaluated by a spectrophotometric method. The quercetin content of the extract was analyzed using the high-performance liquid chromatography (HPLC) method. Antioxidant activity of the extracts was determined by 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity assays. The anti-inflammatory activity was evaluated by the carrageenan-induced paw edema test in the rat. The flavonoid and phenolics contents of Romix® were 50.58 and 265.83 mg/g in ethanol extract and 18.60 and 222.50 mg/g in water extract, respectively. Total quercetin content of Romix® was determined as 2.857 mg/g. Antioxidant activity results showed that et...Continue Reading

References

Jan 1, 1996·Free Radical Biology & Medicine·S A van AckerA Bast
Jan 1, 1996·Free Radical Biology & Medicine·C A Rice-EvansG Paganga
Aug 15, 1998·Journal of Ethnopharmacology·L SeguraS Cañigueral
Oct 9, 1998·Il Farmaco·L E PelzerE Guerreiro
Jul 27, 1999·Life Sciences·G Di CarloF Capasso
Nov 27, 1999·Life Sciences·L BergendiM Ferencik
Dec 1, 1962·Proceedings of the Society for Experimental Biology and Medicine·C A WINTERG W NUSS
Dec 5, 2003·Life Sciences·Keiko MorikawaShigeru Morikawa
Nov 13, 2004·Journal of Pharmacological Sciences·Hyun Pyo KimSam Sik Kang
Mar 9, 2005·Fitoterapia·Nehir UnverH Tansel Ozturk
Apr 1, 1995·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·M Eadie
Apr 1, 1995·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·M Eadie

❮ Previous
Next ❯

Citations

Dec 11, 2014·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Jun WangJianxun Liu

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Acta Crystallographica. Section E, Structure Reports Online
Xiao-Lin GeBan-Feng Ruan
International Journal of Food Sciences and Nutrition
Rashad Rizk Al-HindiMohammad Soror El-Shahawi
American Journal of Surgery
James McGreevy, Deborah Wiebe
© 2021 Meta ULC. All rights reserved