PMID: 9545562Apr 18, 1998Paper

Antioxidant capacity is correlated with steroidogenic status of the corpus luteum during the bovine estrous cycle

Biochimica Et Biophysica Acta
R RapoportI Hanukoglu

Abstract

The reactions of steroid hormone biosynthesis are accompanied by formation of oxygen radicals. We determined the levels of some antioxidants and antioxidative enzymes at different developmental stages of bovine corpora lutea to examine their correlation with steroidogenic status. Plasma progesterone concentrations of estrous cycle synchronized cows increased until day 16, and then decreased rapidly during luteal regression. The levels of steroidogenic cytochrome P450scc and adrenodoxin paralleled the changes in plasma progesterone. Among the antioxidative enzymes examined, the SOD and catalase activities showed patterns most similar to plasma progesterone. Catalase and SOD activities increased 6-8 fold from day 6 to 16 of the estrous cycle and then decreased during the luteal regression. Ascorbate and beta-carotene showed low but significant correlation with P450scc and plasma progesterone levels. The profiles of two lipophilic antioxidants in corpora lutea were very different. beta-carotene concentration increased by approximately 6 fold from day 6 to 16, and decreased in regressive tissue. alpha-tocopherol showed a 3 fold increase between days 6 and 9 followed by a rapid decrease. Thus, at the peak of steroidogenesis at mid-l...Continue Reading

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Citations

Apr 27, 2002·Reproduction in Domestic Animals = Zuchthygiene·S HalilogluZ Bulut
Feb 7, 2013·The Journal of Reproduction and Development·Syota KawaguchiKiyoshi Okuda
Jan 15, 2009·Journal of Animal Physiology and Animal Nutrition·G Arellano-RodriguezA Gonzalez-Bulnes
Nov 23, 2017·The Journal of Clinical Endocrinology and Metabolism·Xintao LiXu Zhang
Feb 13, 2010·Cytometry. Part a : the Journal of the International Society for Analytical Cytology·Berthold LöhrkeTorsten Viergutz
Jul 3, 2020·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Michele R PlewesJohn S Davis
Aug 17, 2018·Reproductive Biology and Endocrinology : RB&E·Hyo-Jin ParkDong-Seok Lee
Mar 7, 2005·Reproductive Medicine and Biology·Norihiro Sugino
Sep 4, 2020·International Journal of Molecular Sciences·Jozef MihalikIngrid Hodorová

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