Antioxidant capacity total in non-melanoma skin cancer and its relationship with food consumption of antioxidant nutrients

Nutrición hospitalaria
Betânia e Silva de Almendra FreitasPatricia Moriel

Abstract

The non-melanoma skin cancer is the most common cancer and accounts for more than half of the diagnoses of cancer, and basal cell carcinoma (BCC), the most frequent cutaneous neoplasm, corresponding to 70-80% of cutaneous tumors. Oxidative stress is an important trigger for skin carcinogenesis. Thus, it is important to evaluate oxidative stress, in order to discern effective therapeutic strategies able to stop it or attenuate it, thereby prevent the installation of non-melanoma skin cancer. Cross-sectional study with controls, involving 84 individuals of both sexes aged between 38-84 years, divided into two groups: control group of healthy people(n = 24) and the case group included individuals who presented non-melanoma skin and they have undergoing surgery (n = 60). The blood samples of the individuals were obtained for evaluation of biomarkers of oxidative stress (F2-isoprostane, nitrite, thiobarbituric acid reactive substances (TBARS) and total antioxidant capacity). The usual dietary intake and nutritional status of the subjects were evaluated. The significance level for this study was 5%. Patients in the case group had higher serum concentrations of biomarkers of oxidative stress, F2-isoprostane concentrations were signifi...Continue Reading

Citations

Nov 20, 2015·Journal of Skin Cancer·Rajani Katta, Danielle Nicole Brown
Apr 18, 2019·Oxidative Medicine and Cellular Longevity·Meghri KaterjiPenelope Duerksen-Hughes

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