Antioxidant defense system, immune response and erythron profile modulation in gold fish, Carassius auratus, after acute manganese treatment

Fish & Shellfish Immunology
Valbona AlikoCaterina Faggio

Abstract

The manganese contamination has become a global problem, recently, because it is perceived as a real threat to the human health and the environment. It is well-known that overexposure to Mn2+ may have negative physiological effects on fish and other organisms inhabiting heavy metal polluted waters. To the best of our knowledge, studies relating with manganese effects on fish antioxidant enzyme response in the blood, immunocompetence and erythron profile alteration, are scarce. In this study, the acute sub-lethal effects of manganese on blood antioxidant response, immune status and erythron profile were determined by exposing the freshwater model organism, Carassius auratus, to two doses of this metal (3.88 ± 0.193 mg/L and 7.52 ± 0.234 mg/L Mn2+) for 96 h. Significant increases in blood antioxidant enzyme activity like superoxide dismutase (SOD), catalase (CAT) and glutathione-S-transferase (GST), were observed in fish exposed to manganese. Furthermore, plasmatic glucose and cortisol levels increased, while total protein decreased significantly. White blood cell differential count revealed a significant increase in monocyte and neutrophil number and a significant decrease of lymphocyte's number in fish exposed to manganese comp...Continue Reading

Citations

Apr 11, 2018·Microscopy Research and Technique·Mohammad Forouhar VajargahCaterina Faggio
Feb 5, 2019·Fish Physiology and Biochemistry·Mohsen Abdel-TawwabCaterina Faggio
Jan 20, 2019·Molecular Reproduction and Development·Donatella Carbone, Caterina Faggio
Aug 26, 2019·Environmental Science and Pollution Research International·Mahmoud A O DawoodMohamed M Abdel-Daim
Dec 12, 2019·Microscopy Research and Technique·Eldores SulaCaterina Faggio
May 3, 2020·Environmental Science and Pollution Research International·Guozhu MaoFaryal Mehr
Nov 12, 2019·Journal of Fish Diseases·Antonio BoxJosé María Valencia
Feb 2, 2020·Environmental Science and Pollution Research International·Mohamed M Abdel-DaimSaad Alkahtani
Jan 12, 2020·Environmental Science and Pollution Research International·Mahmoud A O DawoodMohamed A Aboel-Darag
Jan 10, 2021·Seminars in Cell & Developmental Biology·Qian WuFudi Wang
Jul 14, 2019·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Julio C PainefilúCarlos M Luquet
Aug 9, 2019·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Ahmed Th A IbrahimAntoni Sureda
Jan 26, 2021·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Xiao-Qiang GaoBao-Liang Liu
Dec 7, 2019·The Science of the Total Environment·Josef VaclavikCaterina Faggio
May 26, 2018·Chemosphere·Stefan-Adrian StrungaruGabriel Plavan
Apr 4, 2021·Environmental Toxicology and Pharmacology·Ahmad Mohamadi YalsuyiCaterina Faggio
Oct 31, 2020·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Heba S HamedCaterina Faggio
Apr 27, 2021·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Zhe YuMu-Yang Li
May 8, 2018·The Science of the Total Environment·Pavla SehonovaCaterina Faggio
Jul 3, 2021·Animals : an Open Access Journal From MDPI·Mahmoud S GewailyMahmoud A O Dawood
Aug 8, 2021·Veterinary Research Communications·Mohammad Forouhar VajargahCaterina Faggio
Sep 2, 2021·Brazilian Journal of Biology = Revista Brasleira De Biologia·M M ShahzadL Tahir

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