Antioxidant Lifestyle, Co-Morbidities and Quality of Life Empowerment Concerning Liver Fibrosis

Antioxidants
Diego Martinez-UrbistondoJose Alfredo Martinez

Abstract

The assessment of liver fibrosis has gained importance since the progression of non-alcoholic fatty liver disease (NAFLD). Indeed, the description of the association between undetected liver fibrosis and lifestyle in terms of antioxidant habits, comorbidity and quality of life (QoL) domains may help in the characterization of subjects with NAFLD. A cross-sectional evaluation of (n = 116) consecutive patients from an Internal Medicine ambulatory evaluation was performed. Demographic data, lifestyle, co-morbidity, QoL (according to the SF-36 index) and analytical values to calculate the oxidative related Fibrosis-4 (FIB-4) index were recorded. The association between FIB-4 and co-morbidity, antioxidant habits in QoL was assessed in univariate analysis (p < 0.05) and confirmed in multivariable analysis for 4 of the 8 SF-36 categories: Physical QoL, Physical role, Social QoL and General QoL, as well as in the Physical summary of SF-36 (p < 0.05). Finally, interactions were assessed between co-morbidity, FIB-4 and antioxidant habits showed in the prediction of mean SF-36 (p < 0.01). Liver fibrosis assessed by the oxidative surrogate index FIB-4 is associated with the interaction between antioxidant lifestyle, co-morbidity and physic...Continue Reading

References

Jul 18, 1992·BMJ : British Medical Journal·J E BrazierL Westlake
Feb 15, 2001·The New England Journal of Medicine·A A BravoS Chopra
May 27, 2006·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Richard K SterlingUNKNOWN APRICOT Clinical Investigators
Jun 15, 2007·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Anaïs Vallet-PichardStanislas Pol
May 13, 2009·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Kristin DavidUNKNOWN NASH CRN Research Group
Oct 9, 2009·Antiviral Therapy·Marshall J GlesbyKathryn Anastos
Jun 26, 2010·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Giovanni MussoGianfranco Pagano
Nov 29, 2011·International Journal of Hepatology·Bruce Allen Runyon
Dec 21, 2012·European Journal of Preventive Cardiology·Helen Hermana M HermsdorffJ Alfredo Martínez
Sep 13, 2013·Annals of Internal Medicine·Paul CalèsJérôme Guéchot
Sep 18, 2013·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Jakob B BjornerKate A Miller
Apr 14, 2015·Gastroenterology·Eduardo Vilar-GomezManuel Romero-Gomez
May 20, 2015·PloS One·Jae Yoon ParkUNKNOWN Clinical Research Center for End Stage Renal Disease (CRC for ESRD) Investigators
Sep 18, 2015·Seminars in Liver Disease·Sanjaya K Satapathy, Arun J Sanyal
Jan 20, 2016·Antioxidants·Kyriazoula ChatzianagnostouCristina Vassalle
Jul 28, 2016·Antioxidants & Redox Signaling·Schohraya SpahisEmile Levy
Sep 23, 2016·International Journal of Molecular Sciences·Alessandra CaligiuriFabio Marra
Nov 21, 2017·Journal of Hepatology·Fabio Marra, Gianluca Svegliati-Baroni
May 2, 2018·Journal of Physiology and Biochemistry·Anand Thirupathi, Ricardo A Pinho
Nov 23, 2018·International Journal of Molecular Sciences·Cristina GalarreguiJosé Alfredo Martínez
Dec 19, 2018·Nature Reviews. Gastroenterology & Hepatology·Ramy Younes, Elisabetta Bugianesi
May 3, 2019·Ageing Research Reviews·Tatjana T MakovskiMarjan van den Akker
Nov 21, 2019·Heart Failure Reviews·Mandana MoradiMohammad Raeisi
Nov 22, 2019·Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·F Casas DuranF Ferrer
May 22, 2020·JHEP Reports : Innovation in Hepatology·Lorraine McSweeneyQuentin M Anstee
Jul 28, 2020·Frontiers in Physiology·Mehdi Sharifi-RadJavad Sharifi-Rad
Aug 11, 2020·Oxidative Medicine and Cellular Longevity·Andrés García-SánchezErnesto Germán Cardona-Muñoz
Aug 23, 2020·Antioxidants·Margalida Monserrat-MesquidaAntoni Sureda
Oct 8, 2020·Clínica e investigación en arteriosclerosis : publicación oficial de la Sociedad Española de Arteriosclerosis·Diego Martínez-UrbistondoJose Alfredo Martínez

❮ Previous
Next ❯

Citations

Jul 25, 2021·Journal of Clinical Medicine·Omar Ramos-LopezJ Alfredo Martinez
Oct 10, 2021·Internal and Emergency Medicine·Diego Martínez-UrbistondoUNKNOWN RIETE Investigators

❮ Previous
Next ❯

Methods Mentioned

BETA
biopsy

Software Mentioned

SPSS
ESCAVIDA

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.