Antioxidant Potential of Bark Extracts from Boreal Forest Conifers

Antioxidants
Jean LegaultAndré Pichette

Abstract

The bark of boreal forest conifers has been traditionally used by Native Americans to treat various ailments and diseases. Some of these diseases involve reactive oxygen species (ROS) that can be prevented by the consumption of antioxidants such as phenolic compounds that can be found in medicinal plants. In this study, ultrasonic assisted extraction has been performed under various solvent conditions (water:ethanol mixtures) on the bark of seven boreal forest conifers used by Native Americans including: Pinus strobus, Pinus resinosa, Pinus banksiana, Picea mariana, Picea glauca, Larix laricina, and Abies balsamea. The total phenolic content, as well as ORACFL potency and cellular antioxidant activity (IC50), were evaluated for all bark extracts, and compared with the standardized water extract of Pinus maritima bark (Pycnogenol), which showed clinical efficiency to prevent ROS deleterious effects. The best overall phenolic extraction yield and antioxidant potential was obtained with Picea glauca and Picea mariana. Interestingly, total phenolic content of these bark extracts was similar to Pycnogenol but their antioxidant activity were higher. Moreover, most of the extracts did not inhibit the growth of human skin fibroblasts, ...Continue Reading

References

Jan 1, 1979·Journal of Ethnopharmacology·R F ChandlerS N Hooper
May 1, 1997·Journal of Clinical Periodontology·I L Chapple
Aug 1, 1997·American Journal of Respiratory and Critical Care Medicine·J E RepineI Lankhorst
Jul 4, 2001·American Journal of Respiratory and Critical Care Medicine·C TabakD Kromhout
Nov 13, 2004·Arthritis Research & Therapy·Carol A Hitchon, Hani S El-Gabalawy
Dec 8, 2004·American Journal of Respiratory and Critical Care Medicine·Pierachille SantusAngelo Sala
Jan 11, 2005·The American Journal of Clinical Nutrition·Ilja C W Arts, Peter C H Hollman
Jan 12, 2005·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Benjamin H S LauRay A Barreta
Aug 17, 2005·Current Drug Targets. Inflammation and Allergy·Makoto Nagata
Aug 23, 2005·Proceedings of the American Thoracic Society·William MacNee
Jun 22, 2006·Current Drug Targets·Irfan Rahman, Iain Kilty
Aug 24, 2010·Journal of Ethnopharmacology·Martha-Estrella García-PérezRoxane Pouliot
Sep 8, 2012·Food Chemistry·Martha-Estrella García-PérezTatjana Stevanovic

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Citations

Nov 11, 2014·International Journal of Molecular Sciences·María de la Luz Cádiz-GurreaAntonio Segura-Carretero
Jan 21, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Mathilde MontibusVessela Atanasova
Jun 3, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Kanchan BhardwajKamil Kuča

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