Antioxidant responses to an acute ultra-endurance exercise: impact on DNA stability and indications for an increased need for nutritive antioxidants in the early recovery phase

The British Journal of Nutrition
Oliver NeubauerKarl-Heinz Wagner

Abstract

Antioxidant requirements have neither been defined for endurance nor been defined for ultra-endurance athletes. To verify whether an acute bout of ultra-endurance exercise modifies the need for nutritive antioxidants, we aimed (1) to investigate the changes of endogenous and exogenous antioxidants in response to an Ironman triathlon; (2) to particularise the relevance of antioxidant responses to the indices of oxidatively damaged blood lipids, blood cell compounds and lymphocyte DNA and (3) to examine whether potential time-points of increased susceptibility to oxidative damage are associated with alterations in the antioxidant status. Blood that was collected from forty-two well-trained male athletes 2 d pre-race, immediately post-race, and 1, 5 and 19 d later was sampled. The key findings of the present study are as follows: (1) Immediately post-race, vitamin C, α-tocopherol, and levels of the Trolox equivalent antioxidant capacity, the ferric reducing ability of plasma and the oxygen radical absorbance capacity (ORAC) assays increased significantly. Exercise-induced changes in the plasma antioxidant capacity were associated with changes in uric acid, bilirubin and vitamin C. (2) Significant inverse correlations between ORAC ...Continue Reading

References

Nov 1, 1987·Clinical Science·M GleesonR J Maughan
Aug 1, 1974·Journal of Applied Physiology·D B Dill, D L Costill
Aug 1, 1993·Journal of Applied Physiology·C A ViguieG A Brooks
Apr 19, 1995·JAMA : the Journal of the American Medical Association·I M LeeR S Paffenbarger
Apr 16, 1996·Proceedings of the National Academy of Sciences of the United States of America·M LevineL R Cantilena
Jan 21, 2000·Free Radical Biology & Medicine·R L Prior, G Cao
Feb 25, 2000·Sports Medicine·D J Shaskey, G A Green
Mar 29, 2000·Environmental and Molecular Mutagenesis·R R TiceY F Sasaki
Jun 26, 2001·Annals of Nutrition & Metabolism·R TomaschI Elmadfa
Oct 5, 2001·Free Radical Biology & Medicine·A MastaloudisM G Traber
Apr 19, 2002·Journal of Applied Physiology·David C NiemanJason D Morrow
Jan 16, 2003·European Journal of Applied Physiology·Grégoire P MilletDavid J Bentley
Jan 30, 2004·The British Journal of Nutrition·Stéphane PalazzettiIrène Margaritis
Mar 3, 2004·European Journal of Nutrition·Alfons RamelIbrahim Elmadfa
Mar 9, 2004·Progress in Lipid Research·Y DotanI Pinchuk
Aug 5, 2004·Medicine and Science in Sports and Exercise·David C NiemanChris B Heward
Oct 8, 2004·The British Journal of Nutrition·Anne-Sophie RousseauIrène Margaritis
Feb 15, 2005·Sports Medicine·Asker E JeukendrupLuke Moseley
Dec 17, 2005·Antioxidants & Redox Signaling·Paul W Buehler, Abdu I Alayash
Oct 13, 2006·European Journal of Applied Physiology·Katsuhiko SuzukiPaul B Laursen
Feb 6, 2007·Medicine and Science in Sports and Exercise·Wade L KnezJeff S Coombes
Nov 21, 2007·The British Journal of Nutrition·Jose ViñaConsuelo Borras
Jun 25, 2008·The British Journal of Nutrition·Siegfried KnasmüllerKarl-Heinz Wagner
Jun 13, 2008·European Journal of Applied Physiology·Oliver NeubauerKarl-Heinz Wagner
Aug 19, 2008·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Stefanie ReichholdKarl-Heinz Wagner
Oct 17, 2008·Physiological Reviews·Scott K Powers, Malcolm J Jackson
Nov 5, 2008·Medicine and Science in Sports and Exercise·Oliver NeubauerKarl-Heinz Wagner
Dec 17, 2008·Nutrition Research Reviews·I Margaritis, A S Rousseau
May 13, 2009·Proceedings of the National Academy of Sciences of the United States of America·Michael RistowMatthias Blüher
Jul 11, 2009·Free Radical Research·Stefanie ReichholdKarl-Heinz Wagner
Aug 29, 2009·Archives of Biochemistry and Biophysics·Michalis G Nikolaidis, Athanasios Z Jamurtas

❮ Previous
Next ❯

Citations

Sep 17, 2011·European Journal of Applied Physiology·David S RowlandsM A Tarnopolsky
Nov 28, 2012·European Journal of Applied Physiology·Michael S LustgartenRoger A Fielding
Oct 9, 2014·Sports Medicine·Veronica VleckFrancisco Bessone Alves
Apr 13, 2012·Physiological and Biochemical Zoology : PBZ·Tuul SeppPeeter Hõrak
Jul 29, 2011·Annals of the New York Academy of Sciences·Karl-Heinz WagnerOliver Neubauer
Jul 29, 2011·Annals of the New York Academy of Sciences·Alberto Izzotti
Nov 12, 2013·Journal of Human Nutrition and Dietetics : the Official Journal of the British Dietetic Association·A B SanthakumarI Singh
Jun 16, 2012·Oxidative Medicine and Cellular Longevity·Elisa Couto GomesMarta Rubino de Oliveira
Aug 12, 2014·Biochemical Society Transactions·James E TurnerSarah Aldred
Jan 11, 2014·Journal of Sports Sciences·Athanasios KabasakalisVassilis Mougios
Oct 15, 2013·Journal of Sports Sciences·Ricardo Dantas de LucasAlexandra Latini
Jul 5, 2016·Clinica Chimica Acta; International Journal of Clinical Chemistry·Giuseppe LippiFederico Schena
Apr 12, 2016·Journal of Physical Therapy Science·Jae Hoon RyuHee Tae Roh
Dec 3, 2016·Journal of Applied Physiology·Jonathan M PeakeRichard J Simpson
Nov 23, 2016·Frontiers in Physiology·Feng HeLi Zuo
Mar 31, 2018·American Journal of Physiology. Heart and Circulatory Physiology·Andrew C BulmerJohn P Headrick
Dec 8, 2020·American Journal of Physiology. Endocrinology and Metabolism·Justin F CreedenTerry D Hinds

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Canadian Journal of Applied Physiology = Revue Canadienne De Physiologie Appliquée
Stephane PalazzettiIrene Margaritis
Hepatology : Official Journal of the American Association for the Study of Liver Diseases
Christine GauglhoferBettina Grasl-Kraupp
Molecular Nutrition & Food Research
Nataliya Rohr-UdilovaBettina Grasl-Kraupp
© 2021 Meta ULC. All rights reserved