Antioxidant Status and Risk of Gestational Diabetes Mellitus: a Case-Control Study

Clinical Nutrition Research
Vida Mohammad Parast, Zamzam Paknahad

Abstract

Gestational diabetes mellitus (GDM) is described as glucose intolerance diagnosed during pregnancy. Increased oxidative stress has implicated in diabetic problems. The aim of the current study was to compare antioxidant capacity and antioxidant nutrient intake between women with GDM (n = 40) and healthy pregnant women (n = 40). Demographic and obstetrics data were completed using interview technique and dietary intakes by using a semi-quantitative food frequency questionnaire (FFQ) with 168 items. The total antioxidant capacity (TAC) of serum was assessed by double-antibody sandwich enzyme-linked immune-sorbent assay (ELISA) method. Multivariate logistic regression was performed to compare independent variables and other potential risk factors between 2 groups. The results showed that TAC concentration of serum in women with GDM was significantly lower than in healthy pregnant women (2.3 ± 0.7 vs. 3.7 ± 0.1 µmol/L, p < 0.001). Intakes of vitamin E (11.8 + 3.1 vs. 16.2 + 3.1 mg, p < 0.001), selenium (81 ± 26 vs. 95 ± 36 µg, p < 0.05) and zinc (7.4 ± 1.9 vs. 9.1 ± 1.7 mg, p < 0.001) were significantly lower in women with GDM as compared to healthy pregnant women. In contrast, the groups showed no significant difference in vitamin...Continue Reading

References

May 1, 1993·Metabolism: Clinical and Experimental·G PaolissoF D'Onofrio
Dec 9, 1997·The British Journal of Nutrition·J H BatesD R Hadden
Jun 2, 1998·Free Radical Biology & Medicine·C M SpickettJ McKillop
May 10, 2000·The Journal of Nutrition·R A DiSilvestro
Aug 31, 2000·Gynecologic and Obstetric Investigation·S Kharb
Mar 5, 2003·Journal of Biochemical and Molecular Toxicology·A C MaritimJ B Watkins
Feb 23, 2005·Nutrition·Simona BoGian Franco Pagano
Jul 22, 2005·Current Diabetes Reports·Xinhua Chen, Theresa O Scholl
May 23, 2007·Public Health Nutrition·Parvin MirmiranFereidoun Azizi
Sep 1, 2007·Translational Research : the Journal of Laboratory and Clinical Medicine·Oussama GrissaNaim Akhtar Khan
Sep 2, 2008·Plant Foods for Human Nutrition·In-Cheol JangSeung-Cheol Lee
Jan 20, 2009·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Peter Damm
Jun 8, 2013·Biological Trace Element Research·Samira Behboudi-GandevaniNarges Alian-Moghaddam
Apr 4, 2017·Clinical Medicine : Journal of the Royal College of Physicians of London·Fahmy W HannaAnthony A Fryer

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Citations

Nov 29, 2017·Biological Trace Element Research·Priyanka VermaD N Rao
Feb 13, 2019·Clinical Nutrition Research·Zamzam PaknahadAmir Reza Moravejolahkami
Nov 8, 2018·International Journal of Molecular Sciences·Brittany L Moyce, Vernon W Dolinsky
Aug 21, 2020·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Eleonora SpigolonGiovanna Verlato
Aug 2, 2019·Current Diabetes Reports·Jasmine F PlowsJoanna L Stanley
Oct 22, 2020·International Journal of Environmental Research and Public Health·Dustin W DavisArpita Basu
Oct 2, 2020·Advanced Drug Delivery Reviews·Katherine M NelsonEmily S Day

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Methods Mentioned

BETA
enzyme-linked immune-sorbent assay

Software Mentioned

Nutritionist
Statistical Package for the Social Sciences ( SPSS )

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