Antioxidant supplementation and exhaled nitric oxide in children with asthma

Allergy and Asthma Proceedings
Laura TeneroG L Piacentini

Abstract

The effect of allergen avoidance on airway inflammation is similar to that observed with treatment with inhaled steroids, whereas inhaled steroids have no effect on oxidative stress-induced inflammation. The aim of this study was to retrospectively evaluate the potential effect of an antioxidant dietary supplement on exhaled nitric oxide over a month in pediatric patients on stable antiasthma treatment. Forty-seven children with moderate-to-severe asthma were retrospectively evaluated. All the patients were sensitive to Dermatophagoides pteronyssinus and Dermatophagoides farinae, and they were receiving the minimum inhaled corticosteroid dosage required to maintain adequate control. Within a few weeks of admission at Misurina Hospital in the Alps, the regular treatment was gradually reduced, then some children who were receiving a daily dose of inhaled corticosteroids, ≤200 mcg of fluticasone propionate, were prescribed a nutraceutical dietary supplement for at least 4 weeks. Lung function and fractional exhaled nitric oxide (FeNO) measurements were recorded at the beginning and after 1 month of the dietary supplementation. Baseline lung function and FeNO values did not differ between the two groups of patients. After 4 weeks o...Continue Reading

Citations

Aug 10, 2017·Frontiers in Pediatrics·Milos JesenakEva Babusikova
Apr 10, 2018·Indian Journal of Pediatrics·Jagdish Prasad Goyal, Prawin Kumar
Sep 24, 2016·Allergy & Rhinology·Bhushan ChauhanKomal Chauhan
Dec 17, 2020·The Journal of Nutritional Biochemistry·Lei FangBa Xuan Hoang
Jan 5, 2021·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Francisca de Castro MendesPedro Moreira
Apr 4, 2021·International Journal of Environmental Research and Public Health·Francisca de Castro-MendesPedro Moreira
May 28, 2021·Journal of Family Medicine and Primary Care·Alireza HejratiMaryam Roham
May 22, 2021·Journal of Family Medicine and Primary Care·Seyedeh Reyhaneh Yousefi SharamiFahimeh Nokhostin
Aug 5, 2021·American Journal of Physiology. Lung Cellular and Molecular Physiology·Christopher D PascoeAdrian R West

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