Antioxidant vitamin intake and mortality in three Central and Eastern European urban populations: the HAPIEE study.

European Journal of Nutrition
Urszula StepaniakAndrzej Pajak

Abstract

The aim of the study was to assess the relationships between individual-level dietary intakes of antioxidant vitamins C, E and beta-carotene with all-cause and cause-specific mortality in three Central and Eastern European (CEE) populations. Data from the Health, Alcohol and Psychosocial factors in Eastern Europe cohort study were used. At the baseline survey, between 2002 and 2005, 28,945 men and women aged 45-69 years were examined in Novosibirsk (Russia), Krakow (Poland) and seven Czech towns. Deaths in the cohorts were identified through mortality registers. Cox regression was used to estimate the association between vitamin consumption and all-cause, cardiovascular (CVD) disease and cancer mortality. In multivariable-adjusted analyses, there were no clear inverse associations between antioxidant vitamin intakes and mortality, although in some groups, several hazard ratios (HRs) were significant. For example, in men, compared with the lowest quintile of vitamin C intake, all-cause mortality in the third and fourth quintiles was lower by 28 % (HR 0.72; 95 % CI 0.61-0.85) and by 20 % (HR 0.80; 95 % CI 0.68-0.95), respectively. CVD mortality was lower by 35 % (HR 0.65; 95 % CI 0.50-0.84) and by 23 % (HR 0.77; 95 % CI 0.59-0.99...Continue Reading

References

Dec 15, 1995·American Journal of Epidemiology·D K PandeyJ Stamler
Sep 21, 1994·Journal of the National Cancer Institute·M JainT To
May 20, 1993·The New England Journal of Medicine·M J StampferW C Willett
Sep 1, 1996·American Journal of Epidemiology·N R SahyounR M Russell
Apr 1, 1997·The American Journal of Clinical Nutrition·W C WillettL H Kushi
Aug 2, 2000·The American Journal of Clinical Nutrition·L A YochumL H Kushi
Sep 17, 2002·The Proceedings of the Nutrition Society·Ram Reifen
Feb 6, 2003·Journal of the American College of Nutrition·Sebastian J PadayattyMark Levine
Jun 7, 2003·The American Journal of Clinical Nutrition·Stavroula K OsganianWalter C Willett
Dec 9, 2004·The American Journal of Clinical Nutrition·Paul KnektAlberto Ascherio
Dec 3, 2009·BMC Public Health·Sinéad BoylanMartin Bobak
Jan 27, 2010·The British Journal of Nutrition·Patricia Henríquez-SánchezLluis Serra-Majem
May 18, 2010·International Journal of Cancer. Journal International Du Cancer·Xiaohui CuiSusan E Hankinson
Jan 18, 2011·Current Aging Science·Erin L AbnerRichard J Kryscio
Apr 23, 2011·Stroke; a Journal of Cerebral Circulation·Yoshimi KubotaUNKNOWN JACC Study Group
Jun 15, 2011·Free Radical Biology & Medicine·Maret G Traber, Jan F Stevens
Jul 15, 2011·Economics and Human Biology·Emily M BieleckiBarbara Hulanicka
Apr 11, 2012·Food & Nutrition Research·Nina RoswallAnne Tjønneland
Jun 12, 2012·European Journal of Nutrition·Heiner BoeingBernhard Watzl
May 4, 2013·Critical Reviews in Food Science and Nutrition·J M Landete
Jun 12, 2013·Frontiers in Bioscience (Landmark Edition)·Giuseppe GrossoDiego Gazzolo
May 8, 2014·BioMed Research International·Cheng PengZhen-Yu Chen
Jul 17, 2014·European Journal of Clinical Nutrition·Denes SteflerMartin Bobak

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Citations

Jan 26, 2016·Experimental Gerontology·Pia HorvatMartin Bobak
Jan 17, 2019·Medicinal Research Reviews·Jan MartelJohn D Young
Aug 20, 2019·Platelets·Gennadi Kobzar
Mar 12, 2020·Nutrition & Dietetics : the Journal of the Dietitians Association of Australia·Arpita DasVasant Hirani
May 6, 2017·European Journal of Nutrition·Giuseppe GrossoAndrzej Pajak
Jul 20, 2021·Curēus·Sunil ShahDomonick K Gordon
Aug 28, 2021·Antioxidants·Janusz M Gebicki, Thomas Nauser

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