PMID: 8614611Apr 1, 1996Paper

Antioxidants in pediatric gastrointestinal disease

Pediatric Clinics of North America
R J Sokol, E J Hoffenberg

Abstract

Oxidant stress seems to be involved in the pathogenesis of several important gastroenterologic disorders in infants and children. The question can still be asked, in most circumstances, whether the oxidant stress precedes, and therefore is involved in, tissue or cellular injury or is a result of injury and not of clinical importance. The data favor the former situation in several inflammatory conditions of the bowel and in a variety of liver diseases. Experimental and clinical testing of this possible basic mechanism of tissue injury over the next few years will shed light on the role of antioxidants in treating gastrointestinal disorders.

References

Jul 1, 1977·The Journal of Clinical Investigation·P M FarrellP A di Sant'Agnese
Jan 1, 1992·The Journal of Clinical Investigation·B A Neuschwander-TetriJ H Grendell
Jan 1, 1992·Free Radical Research Communications·R SchreckP A Baeuerle
Jan 1, 1992·Free Radical Biology & Medicine·R NordmannH Rouach
May 1, 1992·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·M A LeoC S Lieber
Jun 1, 1992·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·S KrähenbühlJ Reichen
Feb 1, 1992·The Journal of Clinical Investigation·H M Berschneider, D W Powell
Jan 1, 1991·Free Radical Research Communications·L H Breimer
Dec 1, 1990·Inflammation·M B GrishamE A Deitch
Jan 1, 1990·Alcohol and Alcoholism : International Journal of the Medical Council on Alcoholism·C C CunninghamP I Spach
Feb 1, 1990·Proceedings of the National Academy of Sciences of the United States of America·J S BeckmanB A Freeman
Mar 1, 1990·Gastroenterology·D SandilandsJ M Braganza
Feb 9, 1989·The New England Journal of Medicine·S J Weiss
Apr 14, 1989·Biochemical and Biophysical Research Communications·H Jaeschke, J R Mitchell
Sep 1, 1989·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·J C Caldwell-KenkelJ J Lemasters
Jan 1, 1989·Free Radical Biology & Medicine·J EmeritM Mollet
Apr 1, 1988·Mayo Clinic Proceedings·P A Southorn, G Powis
Aug 1, 1988·Digestive Diseases and Sciences·T KitahoraM Tsuchiya
May 1, 1988·The Journal of Clinical Investigation·X M Sun, W Hsueh
May 1, 1988·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·J MetzgerB H Lauterburg
Oct 1, 1973·Biochemical Medicine·H GreimH Popper
Mar 1, 1983·Digestive Diseases and Sciences·A P KirkJ E Lennard-Jones
Mar 1, 1983·The Journal of Clinical Investigation·B R BaconR O Recknagel
Dec 30, 1993·The New England Journal of Medicine·S Moncada, A Higgs
Aug 7, 1993·Lancet·N K Boughton-SmithS Moncada
Jan 1, 1995·Gastroenterology·B G Rosser, G J Gores
Apr 28, 1994·The New England Journal of Medicine·W Steinberg, S Tenner
Feb 1, 1994·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·S KrähenbühlJ Reichen

❮ Previous
Next ❯

Citations

Mar 9, 2000·Journal of Hepatology·E BroideG Mieli-Vergani
Jun 10, 2004·Journal of Pediatric Gastroenterology and Nutrition·Ronald E KleinmanUNKNOWN North American Society for Pediatric Gastroenterology, Hepatology And Nutrition
Sep 11, 2003·FEBS Letters·Mariarosaria NapolitanoRoberto Rivabene
Jan 27, 2004·The Veterinary Clinics of North America. Equine Practice·Kirsten Tillotson, Josie L Traub-Dargatz
Oct 6, 1998·Scandinavian Journal of Gastroenterology·S N PorterR N Butler

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.