Antioxidative Activity of Colostrum and Human Milk: Effects of Pasteurization and Storage

Journal of Pediatric Gastroenterology and Nutrition
Vesna MarinkovićIvan Spasojević

Abstract

Milk banks collect, pasteurize, and freeze/store human milk. The processing may alter redox properties of milk, but the effects have not been fully examined. We collected 10 mature milk and 10 colostrum samples and applied a battery of biochemical assays and electron paramagnetic resonance spectroscopy to inspect changes that milk undergoes with pasteurization and 30 days storage at -20°C. Pasteurization and storage of raw milk did not affect total nonenzymatic antioxidative capacity, but specific components and features were altered. Urate radical and ascorbyl radical emerge as products of exposure of milk to hydroxyl radical-generating system. Processing shifted the load of antioxidative activity from ascorbate to urate and lowered the capacity of milk to diminish hydroxyl radical. Pasteurization caused a significant drop in the activity of 2 major antioxidative enzymes-superoxide dismutase and glutathione peroxidase, whereas freezing/storage of raw milk affected only superoxide dismutase. Colostrum showed drastically higher total nonenzymatic antioxidative capacity, hydroxyl radical scavenging ability, and glutathione reductase activity compared with mature milk. Pasteurization and storage affect nonenzymatic and enzymatic a...Continue Reading

References

Feb 1, 1988·The American Journal of Clinical Nutrition·A StekelF Pizarro
Feb 1, 1985·The American Journal of Clinical Nutrition·M R BankG Giacoia
May 24, 2000·Journal of Tropical Pediatrics·N A AnkrahC Dzokoto
Nov 23, 2000·Journal of Agricultural and Food Chemistry·H OstdalJ H Nielsen
Aug 25, 2001·Acta Paediatrica·I H BussC C Winterbourn
Sep 11, 2002·FEBS Letters·John X Wilson
Oct 12, 2002·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·A Alberti-FidanzaG Perriello
Feb 3, 2004·Current Pharmaceutical Design·Shaker A Mousa, Ahmed S Mousa
Oct 23, 2004·Archives of Disease in Childhood. Fetal and Neonatal Edition·N HannaT Hegyi
Dec 2, 2004·Nucleosides, Nucleotides & Nucleic Acids·E BusiE Marinello
Jan 25, 2005·BioFactors·María MirandaDolores Silvestre
May 15, 2008·Acta Paediatrica·Dolores SilvestreFrancisco Javier Romero
Oct 25, 2008·Carbohydrate Research·Ivan SpasojevićMihajlo B Spasić
Jan 24, 2009·Clinics in Perinatology·Raghavendra Rao, Michael K Georgieff
Sep 18, 2009·Journal of Human Lactation : Official Journal of International Lactation Consultant Association·Dolores SilvestreFrancisco J Romero
Oct 2, 2009·Journal of Clinical Biochemistry and Nutrition·Asghar ZarbanMohsen Khorashadizadeh
May 27, 2010·Redox Report : Communications in Free Radical Research·Ivan SpasojevićMihajlo B Spasić
Aug 31, 2011·Critical Reviews in Clinical Laboratory Sciences·Ivan Spasojević
Sep 2, 2011·Carbohydrate Research·Jelena Bogdanović PristovIvan Spasojević
Dec 1, 2011·Journal of Clinical Biochemistry and Nutrition·Ingrid Elisia, David D Kitts
Mar 13, 2012·Free Radical Biology & Medicine·Anastasia S DomazouWillem H Koppenol
May 12, 2012·Critical Care : the Official Journal of the Critical Care Forum·Ivan SpasojevićSnežana Spasić
Feb 12, 2013·The Journal of Biological Chemistry·Christopher P CorpeMark Levine
May 11, 2013·The International Journal of Biochemistry & Cell Biology·Dereck E W ChattertonPer Torp Sangild
Apr 23, 2012·Journal of Nutritional Disorders & Therapy·David C DallasJ Bruce German
Jul 23, 2014·Free Radical Biology & Medicine·Darius J R Lane, Des R Richardson
Sep 26, 2014·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Tekin AksuEsin Koç
Mar 15, 2015·Current Opinion in Clinical Nutrition and Metabolic Care·Deborah L O'ConnorSharon Unger
Apr 29, 2015·Breastfeeding Medicine : the Official Journal of the Academy of Breastfeeding Medicine·Asghar ZarbanGholamreza Sharifzadeh

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Citations

Jun 21, 2016·Breastfeeding Medicine : the Official Journal of the Academy of Breastfeeding Medicine·Arthur I Eidelman
Mar 30, 2017·Journal of Trace Elements in Medicine and Biology : Organ of the Society for Minerals and Trace Elements (GMS)·Dijana DjurovićMiroslav Vrvić
Aug 8, 2017·Nutrients·Flaminia BardanzelluAlessandra Reali
Feb 6, 2018·Journal of Dairy Science·André F GuerraRosa H Luchese
Dec 22, 2017·Salud pública de México·Mariana A MarchesinoElio A Soria
Aug 28, 2018·Breastfeeding Medicine : the Official Journal of the Academy of Breastfeeding Medicine·Hannah R Schlotterer, Maryanne T Perrin
Nov 8, 2017·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Won-Ho HahnNam Mi Kang
Jun 9, 2018·Environmental Science and Pollution Research International·Mürsel KarabacakAyça Taş
Aug 10, 2017·Journal of Paediatrics and Child Health·Simeon MinićMiroslav M Vrvić
Feb 14, 2019·BMC Pediatrics·Pasqua PiemonteseFabio Mosca
Aug 14, 2020·Revista paulista de pediatria : orgão oficial da Sociedade de Pediatria de São Paulo·Mariane Fioroti LorençoniMarcio Fronza
Jan 5, 2021·Breastfeeding Medicine : the Official Journal of the Academy of Breastfeeding Medicine·Michelle K McGuirePhilippe Van de Perre
Aug 20, 2019·Prostaglandins, Leukotrienes, and Essential Fatty Acids·Isabell NesselSimon C Dyall
Nov 17, 2017·The Journal of Pediatrics·Annika KloppMeghan B Azad
Mar 29, 2020·Biochemical Pharmacology·Naina MongaAmarjit S Naura

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