Antioxidative activity of furanocoumarins isolated from Angelicae dahuricae

Journal of Ethnopharmacology
Xiang Lan PiaoJeong Hill Park

Abstract

The methylene chloride extract of the root of Angelicae dahuricae showed high protective activity against 2,2'-azobis (2-aminodinopropane) dihydrochloride (AAPH)-induced cellular damage. From this extract, 11 furanocoumarins were isolated, namely oxypeucedanin hydrate, 9-hydroxy-4-methoxypsoralen, byakangelicin, pabulenol, alloisoimperatorin, neobyakangelicol, byakangelicol, oxypeucedanin, imperatorin, phellotorin and isoimperatorin, respectively. Among these 11 furanocoumarins, 9-hydroxy-4-methoxypsoralen and alloisoimperatorin displayed potent antioxidant effects against the DPPH radical and against renal epithelial cell injury by using AAPH to generate peroxyl radicals in vitro.

References

Jan 1, 1990·Free Radical Biology & Medicine·M M DooleyT Nakamura
Jul 15, 1993·European Journal of Biochemistry·H Sies
Mar 1, 1991·Archives of Pharmacal Research·C M KimP Pachaly
Oct 29, 2000·Journal of Agricultural and Food Chemistry·T YokozawaK Kitani

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Citations

Dec 20, 2007·Archives of Pharmacal Research·So Young Kang, Young Choong Kim
Oct 22, 2009·Natural Product Research·Seyed Mehdi RazaviMohammad-Amin Abolghassemi-Fakhri
Feb 19, 2011·Journal of Young Pharmacists : JYP·Ss Sakat, Ar Juvekar
May 13, 2014·Evidence-based Complementary and Alternative Medicine : ECAM·Kao-Sung TsaiWen-Chi Chen
Jun 29, 2015·Free Radical Biology & Medicine·Ranko GacesaPaul F Long
Nov 4, 2010·Toxicology in Vitro : an International Journal Published in Association with BIBRA·Thunchnok JitsanongKanokpan Wongprasert
Aug 5, 2008·Neuroscience Letters·Francesco EpifanoMassimo Curini
Feb 20, 2014·Preventive Nutrition and Food Science·Min-Jung Park, Ji-Sook Han
Mar 29, 2012·Evidence-based Complementary and Alternative Medicine : ECAM·Hoyoung LeeHyeun Kyoo Shin
Jul 14, 2011·European Journal of Pharmacology·Judith SinghuberSteffen Hering
Sep 14, 2016·Ancient Science of Life·Nimisha Pulikkal Sukumaran, R Hiranmai Yadav
Feb 24, 2017·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Lei ZhangXiu-Wei Yang
May 12, 2018·Molecular Nutrition & Food Research·Jing-Jing Zhu, Jian-Guo Jiang
Jul 28, 2016·Phytochemistry Reviews : Proceedings of the Phytochemical Society of Europe·Ewelina Kozioł, Krystyna Skalicka-Woźniak
Sep 2, 2006·Biological & Pharmaceutical Bulletin·Xiang-Lan PiaoShao-Qing Cai
May 17, 2018·Botanical Studies·Wei-Hong LiangYuh-Chyang Charng
Jun 12, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Renato BruniFederica Pellati
Sep 29, 2018·Food Science and Biotechnology·Wei-Hong LiangYuh-Chyang Charng
Sep 5, 2020·Journal of Inflammation Research·Mohammad AlizadehNegin Kamari
Jan 13, 2021·International Journal of Molecular Sciences·Paula Wróblewska-ŁuczkaJarogniew J Łuszczki
Apr 20, 2021·International Journal of Biological Macromolecules·Honglin WangYuanqiang Guo
Aug 29, 2021·Plants·Javad Mottaghipisheh
Nov 1, 2021·Journal of Burn Care & Research : Official Publication of the American Burn Association·Byungsoo KangSeongjun Jo

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