Antioxidative compounds isolated from safflower (Carthamus tinctorius L.) oil cake.

Chemical & Pharmaceutical Bulletin
H L ZhangH Okuyama

Abstract

Seven antioxidative serotonin derivatives were isolated from safflower (Carthamus tinctorius L.) oil cake. Their structures were established as N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]ferulamide (1), N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-p-coumaramide (2), N,N'-[2,2'-(5,5'-dihydroxy-4,4'-bi-1H-indol-3,3'-yl)diethyl]- di-p-coumaramide (3), N-[2-[3'-[2-(p-coumaramido)ethyl]-5,5'-dihydroxy- 4,4'-bi-1H-indol-3-yl]ethyl]ferulamide (4), and N,N'-[2,2'-(5,5'-dihydroxy-4,4'-bi-1H-indol-3,3'-yl)diethyl]- diferulamide (5), N-[2-[5-(beta-D-glucosyloxy)-1H-indol-3-yl)ethyl]- p-coumaramide (6), and N-[2-[5-(beta-D-glucosyloxy)-1H-indol-3-yl)ethyl]ferulamide (7). Antioxidative activities of the compounds were measured by the ferric thiocyanate method and the alpha,alpha-diphenyl-beta-picrylhydrazyl (DPPH) method, and compounds 1-5 were found to have relatively strong antioxidative activity.

Citations

Apr 23, 2013·Journal of Asian Natural Products Research·Jian-Shuang JiangPei-Cheng Zhang
Dec 4, 2010·Vascular Health and Risk Management·Katsuya SuzukiKenji Takazawa
Feb 2, 2013·Chinese Journal of Integrative Medicine·Jinous Asgarpanah, Nastaran Kazemivash
Aug 15, 2012·Natural Product Research·Toshiyuki Takahashi, Mitsuo Miyazawa
Jun 17, 2009·Journal of Ethnopharmacology·Gang ZhaoLi-He Guo
Apr 16, 2016·The American Journal of Chinese Medicine·Le-Le ZhangJin-Jian Lu
Oct 8, 2016·Organic & Biomolecular Chemistry·Kaitlin G HenryElizabeth A Colby Davie
May 31, 2002·Chemical & Pharmaceutical Bulletin·Iclal SaracogluYukio Ogihara
Jun 5, 2002·Chemical & Pharmaceutical Bulletin·U Sebnem HarputYukio Ogihara
Nov 6, 2008·Journal of Asian Natural Products Research·Yu-Zhi ZhouYue-Hu Pei
Sep 24, 2005·Phytotherapy Research : PTR·Anwar H GilaniViqar U Ahmad
Aug 9, 2017·Nutritional Neuroscience·Rosângela Figueiredo Mendes-da-SilvaManuella Batista-de-Oliveira-Hornsby
Jul 24, 2002·Archives of Pharmacal Research·Jun Young LeeSang Won Choi
Sep 15, 2009·The British Journal of Nutrition·Rosaria PigaToshikazu Yoshikawa
Apr 17, 2010·Chemistry & Biodiversity·Chun-Nian HePei-Gen Xiao
Oct 30, 2010·Phytotherapy Research : PTR·Bence CsapiJudit Hohmann
May 9, 2008·Journal of Asian Natural Products Research·Yu-Zhi ZhouYue-Hu Pei
Oct 25, 2011·Phytotherapy Research : PTR·Toshiyuki Takahashi, Mitsuo Miyazawa
Oct 4, 2017·Biological Research·Muhammad AkramAsmat Ullah Khan
Apr 4, 2017·Journal of Neuro-oncology·Diamanto LazariAthanasios P Kyritsis
Jul 11, 1998·Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research·S KawashimaK Onozaki
May 18, 2004·Natural Product Research·Akito NagatsuHajime Mizukami
Jul 24, 2014·Organic & Biomolecular Chemistry·Lachlan M BlairJonathan Sperry
Nov 17, 2020·Journal of Asian Natural Products Research·Hao ZhangPei-Cheng Zhang
Nov 19, 2020·Oxidative Medicine and Cellular Longevity·Ikram KhémiriLotfi Bitri
Feb 23, 2010·Organic Letters·Jian-Shuang JiangPei-Cheng Zhang
Feb 24, 2015·Organic Letters·Emily M Boyd, Jonathan Sperry
Oct 11, 2017·Journal of Agricultural and Food Chemistry·Xing-Rong PengMing-Hua Qiu

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