PMID: 29845960May 31, 2018Paper

Antiphospholipid Syndrome Complicating Pneumococcal Meningitis

Indian Pediatrics
Suresh MekalaReena Gulati

Abstract

Antiphospholipid syndrome is a multisystem auto-immune disorder characterized by arterial or venous thrombosis in children. 11-year-old child with pneumococcal meningitis also had cerebral sinus vein thrombosis and pulmonary artery segmental thrombosis. Pro-thrombotic evaluation showed positive lupus anticoagulant at baseline and after 12 weeks. Investigations for lupus were negative at admission and after one year of follow-up. Antiphospholipid syndrome is a possibility even in thrombosis occurring in the setting of meningitis.

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Autoimmune Diseases

Autoimmune diseases occur as a result of an attack by the immune system on the body’s own tissues resulting in damage and dysfunction. There are different types of autoimmune diseases, in which there is a complex and unknown interaction between genetics and the environment. Discover the latest research on autoimmune diseases here.

Antiphospholipid Syndrome

Antiphospholipid syndrome or antiphospholipid antibody syndrome (APS or APLS), is an autoimmune, hypercoagulable state caused by the presence of antibodies directed against phospholipids.

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