Antiphospholipid syndrome: role of antiphospholipid antibodies in neurology

Hematology/oncology Clinics of North America
Rima M Dafer, José Biller

Abstract

Antiphospholipid antibodies (aPLs) are acquired antibodies against anionic phospholipid containing moieties in cell membranes. Their presence often is associated with the antiphospholipid syndrome (APS), an acquired autoimmune prothrombotic syndrome associated with thrombosis in the arterial and venous circulations, recurrent unexplained fetal loss, and thrombocytopenia. The association of aPLs with other nonthrombotic neurological disorders remains of unclear significance. This article reviews the definition of APS, its clinical presentations, and therapeutic approaches.

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Citations

Nov 26, 2013·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Doniel DrazinWouter Schievink
Aug 30, 2008·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Simona VelicuFred Leya
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Nov 21, 2020·Biomedicines·Amine Ghembaza, David Saadoun

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