PMID: 9174974Apr 1, 1997Paper

Antiplasmodial activity of four Kenyan medicinal plants

Journal of Ethnopharmacology
E OmulokoliS C Chhabra

Abstract

A preliminary antiplasmodial and phytochemical screening of four Kenyan medicinal plants was carried out. The medicinal plants were extracted and tested for in vitro antiplasmodial activity against chloroquine-sensitive (K67) and chloroquine-resistant (ENT36) strains of Plasmodium falciparum. Out of 16 extracts, 12 were active against ENT36 strain while seven were active against K67 strain, that is, IC50 < or = 50 micrograms/ml. The most active extracts on both strains were those of leaves of Phyllanthus reticulatus Poir, and Suregada zanzibariensis Baill. (Euphorbiaceae) with IC50 < or = 10 micrograms/ml. The stembark of Terminalia spinosa Engl. (Combretaceae) and the stems of Dissotis brazzae Cogn. (Melastomataceae) had IC50 < or = 10 micrograms/ml for strains K67 and ENT36, respectively. A preliminary phytochemical analysis of these plants revealed the presence of different classes of primary and secondary metabolites.

References

Dec 1, 1979·Antimicrobial Agents and Chemotherapy·R E DesjardinsJ D Chulay
Aug 1, 1987·Journal of Ethnopharmacology·G A Kyerematen, E O Ogunlana
Jul 1, 1984·Journal of Ethnopharmacology·S C ChhabraE N Mshiu
Jun 1, 1994·Transactions of the Royal Society of Tropical Medicine and Hygiene·J D Phillipson

❮ Previous
Next ❯

Citations

Nov 17, 2010·Parasitology Research·Asokan BagavanDinkar Sahal
Feb 27, 2013·Archives of Pharmacal Research·Keyong Ho Lee, Ki-Hyeong Rhee
Dec 31, 2003·Journal of Ethnopharmacology·G N WanyoikeS A Omar
Apr 9, 2005·Journal of Ethnopharmacology·Guédé Noël ZirihiPhilippe Grellier
Sep 1, 2000·Journal of Ethnopharmacology·G del Barrio, F Parra
Oct 12, 2000·Journal of Ethnopharmacology· MustofaM Mallié
Aug 29, 2012·Journal of Asian Natural Products Research·Jian-Xiong MaDa-Yuan Zhu
Aug 10, 2004·Journal of Medicinal Food·Ganesh Chandra Jagetia, Manjeshwar Shrinath Baliga
Sep 1, 2009·Journal of Ethnobiology and Ethnomedicine·Mainen J MoshiAnke Weisheit
Dec 15, 2010·Journal of Ethnobiology and Ethnomedicine·Ripu M KunwarRainer W Bussmann
Feb 8, 2008·Journal of Zhejiang University. Science. B·Firas A Al-Bayati, Hassan F Al-Mola
Nov 5, 2014·Jundishapur Journal of Microbiology·Fariba KhoshzabanHamid Reza Jamshidi Koohsari
Oct 10, 2014·BioMed Research International·Abhinav UpadhyayKumar Venkitanarayanan
Jan 26, 2010·Journal of Ethnopharmacology·J M NgutaS G Kiama
Sep 19, 2009·Journal of Ethnopharmacology·Alex Asase, Gloria Oppong-Mensah
Apr 29, 2009·Journal of Ethnopharmacology·Belsem MarzoukMahjoub Aouni
Mar 13, 2012·Phytotherapy Research : PTR·Venkata Siva Satyanarayana Kantamreddi, Colin W Wright
Jul 22, 2010·Pharmaceutical Biology·Nuch PojchaijongdeeOnoomar Poobrasert
Apr 17, 2015·BMC Complementary and Alternative Medicine·Ahmed RezkMatthias S Ullrich
Dec 30, 2008·Journal of Bioscience and Bioengineering·Adithepchaikarn PachanawanPongsak Rattanachaikunsopon
May 21, 2016·Evidence-based Complementary and Alternative Medicine : ECAM·Xin MaoLan-Zhen Zhang
Jan 6, 2000·Toxicology and Applied Pharmacology·A Sànchez-LamarR De Salvia
Dec 2, 2008·Journal of Ethnopharmacology·G M RukungaW M Kofi-Tsekpo
Jun 9, 2009·Journal of Ethnopharmacology·Elizabeth V M KigonduIsaiah O Ndiege
Oct 13, 2004·Phytotherapy Research : PTR·Philippe RasoanaivoFrançois Frappier
Aug 16, 2005·Journal of Ethnopharmacology·Finn SandbergHesham Rushdey El-Seedi
Dec 30, 2010·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Abdulelah H Al-AdhroeyRohela Mahmud
Feb 2, 2018·BMC Complementary and Alternative Medicine·Saima AliZartash Zahra
May 16, 2007·Phytochemical Analysis : PCA·Sio-Hong LamShoei-Sheng Lee
Jan 11, 2018·Polish Journal of Microbiology·Monika CiochTomasz Tarko
Jul 4, 2020·Evidence-based Complementary and Alternative Medicine : ECAM·Timothy Omara
Mar 28, 2017·BMC Complementary and Alternative Medicine·Ramadhani Selemani Omari NondoDenis Zofou
Jul 10, 2020·Natural Product Research·Thuc-Huy DuongJirapast Sichaem
Jan 30, 2010·Natural Product Reports·Muhammad SaleemAbdul Jabbar

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antimalarial Agents

Antimalarial agents, also known as antimalarials, are designed to prevent or cure malaria. Discover the latest research on antimalarial agents here.

Antimalarial Agents (ASM)

Antimalarial agents, also known as antimalarials, are designed to prevent or cure malaria. Discover the latest research on antimalarial agents here.