PMID: 6413980Aug 1, 1983Paper

Antipsoriatic drugs as inhibitors of soybean lipoxygenase. A possible mode of action

Prostaglandins, Leukotrienes, and Medicine
J C Sircar, C F Schwender

Abstract

Eight known antipsoriatic drugs of diverse structures were tested on the basis of their structural similarity with arachidonic acid and known inhibitors of lipoxygenase. A correlation was observed between their antipsoriatic activity and lipoxygenase inhibition suggesting that a common underlying mechanism of action might be involved.

References

Aug 1, 1979·The Journal of Investigative Dermatology·S HammarströmJ J Voorhees
Sep 21, 1976·Biochemistry·M J Gibian, R A Galaway
Dec 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·S HammarströmJ J Voorhees
Oct 1, 1973·Biochemical and Biophysical Research Communications·M R EgmondJ Boldingh
Jun 19, 1982·Lancet·C HindsonH Wacks
Oct 2, 1982·Lancet·S D BrainM W Greaves
Dec 25, 1982·Lancet·J GrabbeM Mardin
Jan 1, 1983·The Journal of Pharmacy and Pharmacology·J HarveyW Dawson
Feb 27, 1981·Annals of the New York Academy of Sciences·D H Russell, M K Haddox
Mar 1, 1981·British Journal of Pharmacology·M A BrayM J Smith
Aug 1, 1981·Prostaglandins·M A BrayM J Smith
Mar 1, 1983·Prostaglandins·J C SircarE A Johnson
Jul 1, 1981·Archives of Dermatology·J J Voorhees, C E Orfanos
Oct 30, 1982·British Medical Journal·B R Allen, S M Littlewood
Nov 13, 1982·British Medical Journal
Oct 1, 1980·Archives of Dermatology·D KohnF Zuckerman
Jan 1, 1981·Pharmacology & Therapeutics·C J McDonald
Aug 1, 1981·The British Journal of Dermatology·H Ippen
Oct 1, 1980·The British Journal of Dermatology·G Michaëlsson
Feb 1, 1953·Archives of Biochemistry and Biophysics·A L TAPPELP D BOYER
Dec 1, 1962·Archives of Biochemistry and Biophysics·E VIOQUE, R T HOLMAN

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Citations

Nov 1, 1986·Prostaglandins, Leukotrienes, and Medicine·G B Skeggs, W R Murray
Jan 15, 2005·Journal of the European Academy of Dermatology and Venereology : JEADV·V SchleyerR-M Szeimies
May 1, 1986·The British Journal of Dermatology·P D MauriceP C Bather
Jan 1, 1986·The British Journal of Dermatology·P D MauriceB R Allen
Apr 1, 1987·Biochemical Pharmacology·R Müller-Peddinghaus, M Wurl

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