PMID: 6769972Mar 1, 1980

Antiseptic and antibiotic resistance in Gram-negative bacteria causing urinary tract infection

Journal of Clinical Pathology
D J Stickler, B Thomas

Abstract

A collection of 802 isolates of Gram-negative bacteria causing urinary tract infections was made from general practice, antenatal clinics, and local hospitals. The organisms were tested for their sensitivity to chlorhexidine, cetrimide, glutaraldehyde, phenyl mercuric nitrate, a phenolic formulation, and a proprietary antiseptic containing a mixture of picloxydine, octyl phenoxy polyethoxyethanol, and benzalkonium chloride. Escherichia coli, the major species isolated, proved to be uniformly sensitive to these agents. Approximately 10% of the total number of isolates, however, exhibited a degree of resistance to the cationic agents. These resistant organisms were members of the genera Proteus, Providencia, and Pseudomonas; they were also generally resistant to five, six, or seven antibiotics. It is proposed therefore that an antiseptic policy which involves the intensive use of cationic antiseptics might lead to the selection of a flora of notoriously drug-resistant species.

References

Apr 1, 1978·Antimicrobial Agents and Chemotherapy·L Sutton, G A Jacoby
Oct 1, 1978·Journal of Clinical Pathology·B ThomasD J Stickler
Sep 1, 1976·Journal of Clinical Pathology·D J Stickler, B Thomas
Feb 26, 1972·Lancet·J D O'Flynn, D J Stickler
Apr 1, 1974·Journal of Clinical Pathology·D J Stickler
Jul 8, 1967·British Medical Journal·W A GillespieG A Phippen
Jun 1, 1954·British Journal of Pharmacology and Chemotherapy·G E DAVIESG SWAIN

Citations

Sep 1, 1986·The Journal of Hospital Infection·C FawcettD J Stickler
Sep 25, 2003·The Journal of Hospital Infection·E MartróV Ausina
Jan 14, 2003·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·Maan Singh SidhuAskild Holck
Apr 15, 2003·Clinical Microbiology Reviews·Peter Gilbert, Andrew J McBain
Oct 19, 2004·Clinical Microbiology Reviews·Günter Kampf, Axel Kramer
Aug 1, 1996·The British Journal of Ophthalmology·J Hay, D V Seal
Apr 1, 1984·Journal of Clinical Pathology·M H LevinR A Weinstein
Nov 26, 2010·Journal of Periodontology·Ahmed Y GamalMahmoud T El Destawy
May 15, 2007·The Journal of Hospital Infection·H WisplinghoffH Seifert
Jun 17, 2003·Journal of Applied Microbiology·S LangsrudG Sundheim
Nov 1, 1987·The Journal of Hospital Infection·D J Stickler, J C Chawla
Jul 1, 1987·The Journal of Hospital Infection·D A DanceJ A Lowes
Jul 1, 1987·The Journal of Hospital Infection·D J SticklerJ C Chawla
Jul 1, 1987·The Journal of Hospital Infection·L Baillie
Dec 1, 1980·The Journal of Hospital Infection·M T CafferkeyD Murphy
Jun 1, 1983·The Journal of Hospital Infection·T L PittP N Hoffman
Mar 1, 1982·The Journal of Hospital Infection·C L ClaytonD J Stickler
May 1, 1986·The Journal of Hospital Infection·A D RussellJ R Morgan
Dec 1, 1982·The Journal of Hospital Infection·M F NoyL L Watterson
Oct 1, 1986·Journal of Clinical and Hospital Pharmacy·W N Cottrell, R W Fitzpatrick
Oct 1, 1988·British Journal of Urology·J C ChawlaD J Stickler
Nov 1, 1986·The Journal of Applied Bacteriology·N IsmaeelA D Russell
Apr 1, 1986·The Journal of Applied Bacteriology·N IsmaeelA D Russell
Jan 1, 1988·Society for Applied Bacteriology Symposium Series·A D Russell, G W Gould
May 19, 2001·The Journal of Hospital Infection·S M MurtoughA D Russell
Jul 2, 2002·The Journal of Hospital Infection·S KõljalgM Mikelsaar
Jul 10, 2001·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·C S HigginsT R Walsh
Sep 11, 2004·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Shubhangi Bhende, Daniel Spangler
May 1, 1986·The Journal of Applied Bacteriology·B Holmes
Apr 11, 2019·Frontiers in Microbiology·Fabian CieplikAli Al-Ahmad
Apr 1, 1983·The Journal of Urology·F R FalkinerW A Gillespie

Related Concepts

Microbicides, Topical
Antibiotics
Tubulicid
Antibiotic Resistance, Microbial
Paracolobactrum
Alkalescens-Dispar Group
Sekumatic
Klebsiella
Phenols
Phenylmercury Compounds

Related Feeds

Allergy & Infectious Diseases

Allergies result from the hyperreactivity of the immune system to some environmental substance and can be life-threatening. Infectious diseases are caused by organisms including bacteria, viruses, fungi and parasites. They can be transmitted different ways, such as person-to-person. Here is the latest research on allergy and infectious diseases.

Allergy & Infectious Diseases (ASM)

Allergies result from the hyperreactivity of the immune system to some environmental substance and can be life-threatening. Infectious diseases are caused by organisms including bacteria, viruses, fungi and parasites. They can be transmitted different ways, such as person-to-person. Here is the latest research on allergy and infectious diseases.

Antimicrobial Resistance (ASM)

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.

Antimicrobial Resistance

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.