PMID: 9181693Jun 15, 1997Paper

Antiserum to the egg coats of the fat-tailed dunnart (Marsupialia, Dasyuridae) cross-reacts with egg coats of other marsupial and eutherian species

The Journal of Experimental Zoology
C T RobertsW G Breed

Abstract

We are examining the extracellular coats of the brush-tailed possum as a possible target for an immunocontraceptive vaccine for biocontrol of this pest species in New Zealand. In this study we have compared the composition of the extracellular coats of the fat-tailed and stripe-faced dunnarts, brush-tailed possum, domestic rabbit, and laboratory mouse using histochemistry, immunocytochemistry, and immunofluorescence. The histochemistry of the luminal epithelium of the oviduct and mucoid coats of the marsupials and rabbit indicated that they contain acidic glycoproteins. Immunofluorescence showed that polyclonal antiserum raised against the extracellular coats of the oocyte and early embryo of the fat-tailed dunnart, cross-reacted with the extracellular coats of the oocytes of all five species. These results suggest that there are common epitopes on the extracellular coats of oocytes and early embryos of distinctly related therian species. Further work to characterise these proteins is required to determine whether there is close homology between the oviductal glycoproteins of these species.

References

Jan 1, 1992·Current Topics in Developmental Biology·L Selwood
Jul 1, 1988·Journal of Reproduction and Fertility·J C Rodger, K E Mate
Jun 1, 1969·Biology of Reproduction·L K Brower, E Anderson
Jul 1, 1974·Journal of Reproduction and Fertility·R L Hughes
Feb 1, 1982·Biology of Reproduction·R P Jansen, V K Bajpai
Nov 1, 1994·The Journal of Experimental Zoology·C T RobertsG Mayrhofer
Jan 1, 1993·Reproduction, Fertility, and Development·F GandolfiA Lauria
Apr 1, 1996·Cell and Tissue Research·C T Roberts, W G Breed
Feb 1, 1996·Molecular Reproduction and Development·H Murakami, H Imai
Jan 1, 1996·Reproduction, Fertility, and Development·P E Cowan
Jan 1, 1961·Fertility and Sterility·G S GREENWALD

❮ Previous
Next ❯

Citations

Jul 11, 2008·Biology of Reproduction·Ellen Menkhorst, Lynne Selwood
May 2, 2002·Molecular Reproduction and Development·Nicholas P CaseyLynne Selwood
Feb 16, 2006·Reproduction, Fertility, and Development·Richard R BehringerMarilyn B Renfree

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antibody Specificity

Antibodies produced by B cells are highly specific for antigen as a result of random gene recombination and somatic hypermutation and affinity maturation. As the main effector of the humoral immune system, antibodies can neutralize foreign cells. Find the latest research on antibody specificity here.