PMID: 15334357Jan 1, 1987Paper

Antithrombin III (ATIII) activity in plasmas from normal and diseased horses, and in normal canine, bovine and human plasmas

Veterinary Clinical Pathology
I B JohnstoneS Crane

Abstract

Plasma Antithrombin III (ATIII) activity was quantitated in 24 clinically normal Standardbred/Thoroughbred horses using a clotting time technique. ATIII activity ranged from 80 to 106% of the pooled reference standard plasma, with a mean of 94%. Horses presenting with impaction or spasmotic colic (n=17) had normal plasma ATIII activity, while 15 horses presenting with acute diarrhea/colitis had significantly lower plasma ATIII activity with a mean of only 74% of the reference plasma. Seven horses presenting with liver disease had significantly higher plasma ATIII activity with a range of 127 to 177% of the pooled reference plasma. Fifty-seven equine plasmas were retested using a rapid chromogenic substrate technique for quantitating plasma ATIII activity. A good correlation (r =+0.83) existed between clotting time and chromogenic determinations of ATIII. Pooled normal canine, human and bovine plasmas had only 65, 62 and 79%, respectively, of the ATIII activity of the equine reference plasma.

References

Mar 11, 1978·Lancet
Sep 1, 1979·Proceedings of the Society for Experimental Biology and Medicine·S L Raymond, W J Dodds
May 1, 1979·Scandinavian Journal of Haematology·K A Jørgensen, E Stoffersen
Jul 1, 1986·Equine Veterinary Journal·I B Johnstone, S Crane
Feb 15, 1985·Thrombosis Research·J Z MortensenT Arnfred
Jan 1, 1985·Haemostasis·M E Eyster, M E Parker
Aug 1, 1985·American Journal of Clinical Pathology·V M NapoliJ L Newton
Oct 1, 1985·Seminars in Thrombosis and Hemostasis·E F MammenG Murano
Nov 1, 1974·Thrombosis Research·M BlombäckL Svendsen
Mar 1, 1984·European Journal of Cancer & Clinical Oncology·A Moore
Jun 1, 1984·Annals of Internal Medicine·O D RatnoffJ Jenkins
Oct 1, 1983·American Journal of Clinical Pathology·R K Ito, B E Statland
Jan 1, 1984·Transfusion·M InksterL W Gaston
Jan 1, 1982·British Journal of Haematology·R D Philo, P J Gaffney
Apr 1, 1981·Annals of Internal Medicine·P M Ness
Apr 1, 1980·American Journal of Clinical Pathology·P G KingV L Farris

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Citations

Jan 1, 1992·Veterinary Clinical Pathology·Carol P. MandellBernard F. Feldman
Jan 1, 1993·Veterinary Clinical Pathology·C. B. Andreasen, S. Lovelady
Jan 1, 1994·Journal of Veterinary Internal Medicine·B R Moore, K W Hinchcliff
May 1, 1991·Equine Veterinary Journal·B J DarienJ Travis
Feb 14, 2019·Expert Review of Neurotherapeutics·Pan ChenMichael Aschner
Mar 1, 1996·The Veterinary Quarterly·W Misdorp
Jan 4, 1997·The Veterinary Record·N PusterlaH Lutz

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