Antithrombotic Therapy for Venous Thromboembolism and Prevention of Thrombosis in Otolaryngology-Head and Neck Surgery: State of the Art Review

Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery
John D CramerMichael J Brenner

Abstract

Objective The aim of this report is to present a cohesive evidence-based approach to reducing venous thromboembolism (VTE) in otolaryngology-head and neck surgery. VTE prevention includes deep venous thrombosis and pulmonary embolism. Despite national efforts in VTE prevention, guidelines do not exist for otolaryngology-head and neck surgery in the United States. Data Sources PubMed/MEDLINE. Review Methods A comprehensive review of literature pertaining to VTE in otolaryngology-head and neck surgery was performed, identifying data on incidence of thrombotic complications and the outcomes of regimens for thromboprophylaxis. Data were then synthesized and compared with other surgical specialties. Conclusions We identified 29 articles: 1 prospective cohort study and 28 retrospective studies. The overall prevalence of VTE in otolaryngology appears lower than that of most other surgical specialties. The Caprini system allows effective individualized risk stratification for VTE prevention in otolaryngology. Mechanical and chemoprophylaxis ("dual thromboprophylaxis") is recommended for patients with a Caprini score ≥7 or patients with a Caprini score of 5 or 6 who undergo major head and neck surgery, when prolonged hospital stay is an...Continue Reading

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Citations

Jan 24, 2019·Journal of Perioperative Practice·Tristan Tham, Peter Costantino
Jun 20, 2019·International Journal of Molecular Sciences·Pierre HaenLaurence Panicot-Dubois
Sep 23, 2020·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Kara D MeisterMichael J Brenner
Aug 12, 2018·JAMA Otolaryngology-- Head & Neck Surgery·Sara Juliana de A de VasconcellosPaulo Ricardo Saquete Martins-Filho
Jan 22, 2021·Vestnik otorinolaringologii·A V Varvyanskaya, A S Lopatin
Dec 6, 2020·Mayo Clinic Proceedings·Matthew A BartlettPaul R Daniels
Apr 21, 2021·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Taylor C StandifordJeffrey E Terrell
Jul 14, 2021·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Lirit LeviAviram Mizrachi

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