Antithrombotic therapy in peripheral artery disease

Vascular Medicine
T Raymond FoleyEhrin J Armstrong

Abstract

Antiplatelet agents are recommended for the reduction of major adverse cardiovascular events among all patients with symptomatic peripheral artery disease. However, the optimal antiplatelet regimen and duration of therapy in peripheral artery disease (PAD) remains unclear, largely due to limited and conflicting data in this patient population. This article reviews current data on antithrombotic therapy in PAD and discusses the implications of this data for current practice and future research.

References

Jan 23, 1992·The New England Journal of Medicine·V FusterJ H Chesebro
May 12, 1998·Journal of Vascular Surgery·L A KillewichW R Flinn
Oct 12, 1999·Circulation·M J Quinn, D J Fitzgerald
Jun 8, 2000·Journal of Vascular Surgery·R J PowellJ L Cronenwett
Jan 2, 2001·Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis·F ZeigerM Koksch
Aug 25, 2001·The New England Journal of Medicine·S YusufUNKNOWN Clopidogrel in Unstable Angina to Prevent Recurrent Events Trial Investigators
Sep 19, 2001·JAMA : the Journal of the American Medical Association·A T HirschW R Hiatt
Oct 25, 2001·Lancet·K Ouriel
Nov 19, 2002·JAMA : the Journal of the American Medical Association·Steven R SteinhublUNKNOWN CREDO Investigators. Clopidogrel for the Reduction of Events During Observation
Jan 15, 2003·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·P A RoblessG P Stansby
Jun 25, 2003·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Paul BarraganMartin Eigenthaler
Jul 5, 2003·Journal of Vascular Surgery·K CassarJ Brittenden
Oct 12, 2004·European Heart Journal·Gian Gastone Neri SerneriUNKNOWN Drug Evaluation in Atherosclerotic Vascular Disease in Diabetics (DAVID) Study Group
Mar 11, 2005·The New England Journal of Medicine·Marc S SabatineUNKNOWN CLARITY-TIMI 28 Investigators
Apr 22, 2005·The New England Journal of Medicine·Göran K Hansson
Aug 9, 2005·American Heart Journal·Daniel G HackamSonia S Anand
Nov 8, 2005·Lancet·Z M ChenUNKNOWN COMMIT (ClOpidogrel and Metoprolol in Myocardial Infarction Trial) collaborative group
Dec 3, 2005·The Journal of Clinical Investigation·Meinrad GawazAndreas E May
Jan 13, 2006·JAMA : the Journal of the American Medical Association·Deepak L BhattUNKNOWN REACH Registry Investigators
Mar 15, 2006·The New England Journal of Medicine·Deepak L BhattUNKNOWN CHARISMA Investigators
Mar 22, 2006·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·K CassarJ Brittenden
Aug 16, 2006·Circulation·Beatrice A GolombMichael H Criqui
Sep 12, 2006·Journal of Thrombosis and Haemostasis : JTH·G Agnelli, C Becattini
Feb 20, 2007·Journal of Internal Medicine·UNKNOWN Critical Leg Ischaemia Prevention Study (CLIPS) GroupR Peto
Mar 27, 2007·American Journal of Preventive Medicine·Matthew A AllisonMichael H Criqui
Jun 23, 2007·Circulation Research·Zaverio M Ruggeri, G Loredana Mendolicchio
Jul 20, 2007·The New England Journal of Medicine·UNKNOWN Warfarin Antiplatelet Vascular Evaluation Trial InvestigatorsGilbert Gosselin
Nov 6, 2007·Journal of the American College of Cardiology·Paul A GurbelAlan D Michelson
Dec 14, 2007·The New England Journal of Medicine·Giovanni Davì, Carlo Patrono
Nov 18, 2008·European Journal of Internal Medicine·Massimo Franchini, Pier Mannuccio Mannucci
Jan 13, 2009·European Heart Journal·Patrice P CacoubUNKNOWN CHARISMA Investigators
May 14, 2009·JAMA : the Journal of the American Medical Association·Jeffrey S BergerWilliam R Hiatt
Sep 1, 2009·The New England Journal of Medicine·Lars WallentinMona Thorsén
Nov 11, 2009·Circulation·Curt DiehmUNKNOWN German Epidemiological Trial on Ankle Brachial Index Study Group
Jan 27, 2010·Pharmacotherapy·Mori J KrantzWilliam R Hiatt

❮ Previous
Next ❯

Citations

Jul 19, 2016·Atherosclerosis·Geoffrey D Barnes, Elizabeth A Jackson
Nov 22, 2017·VASA. Zeitschrift für Gefässkrankheiten·Dan-Mircea OlinicMaria Olinic
Jul 12, 2018·Current Cardiology Reports·Eric W RudofkerEhrin J Armstrong
Feb 22, 2021·American Journal of Cardiovascular Drugs : Drugs, Devices, and Other Interventions·Kristin R Hand, Genevieve M Hale

❮ Previous
Next ❯

Methods Mentioned

BETA
flow cytometry
CLIPS
genotyping
amputation
amputations

Software Mentioned

CAPRIE
POPADAD

Related Concepts

Related Feeds

Blood Clotting Disorders

Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.

Blood Coagulation Signaling Pathways

Coagulation is the process by which a blood clot is formed. This process includes both the formation of a platelet plug as well as a cascade of clotting factors resulting in the formation of fibrin strands. Find the latest research on coagulation signaling pathways here.